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This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 
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:: Volume 24, Issue 1 (3-2022) ::
J Babol Univ Med Sci. 2022; Volume 24 Back to browse issues page
Vitamin D Levels and Risk of Retinopathy in Patients with Diabetes Mellitus
SA Rasoulinejad , A Akbari *
2.Department of Physiology, School of Veterinary Medicine, Shiraz University, Shiraz, I.R.Iran. , akbariabolfazl@gmail.com
Abstract:   (1410 Views)
Background and Objective: Epidemiological data show a strong correlation between vitamin D deficiency and the incidence of diabetes mellitus. Many studies have reported hypovitaminosis D in patients with diabetic retinopathy, and it is possible that the deficiency of this vitamin plays a role in the pathogenesis of this diabetic complication. Therefore, the aim of this study is to investigate the serum levels of vitamin D in patients with diabetic retinopathy and its relationship with the prevalence of diabetic retinopathy.
Methods: In this review article, we searched Scopus, Google Scholar, and PubMed databases using the keywords vitamin D deficiency, serum vitamin D levels, vitamin D supplement, diabetes, and diabetic retinopathy. No time limit was considered for the search. Articles written in English were included in this study. Original and complete articles in English about vitamin D deficiency, diabetes and retinopathy were reviewed. Review articles and animal studies were excluded from this study. The data obtained from these findings were extracted and evaluated by two reviewers.
Findings: In this study, out of 52 studies found, 15 articles were reviewed according to the inclusion criteria. The results showed that vitamin D deficiency is very common in people with diabetes and diabetic retinopathy and there is a strong inverse relationship between vitamin D deficiency and diabetic retinopathy. In addition, the use of its supplements is also necessary to prevent the progression of diabetic retinopathy.
Conclusion: The results of this study suggest that the reduction of vitamin D serum levels is very common in patients with diabetic retinopathy and can be one of the risk factors for developing retinopathy. Its plasma level can have a high diagnostic value in order to prevent and control the onset of this complication.
Keywords: Vitamin D Deficiency, Vitamin D Serum Level, Vitamin D Supplement, Diabetes and Diabetic Retinopathy.
Full-Text [PDF 337 kb]   (417 Downloads)    
Type of Study: Review | Subject: Physiology
Received: 2022/05/26 | Accepted: 2022/06/27 | Published: 2022/07/9
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Rasoulinejad S, Akbari A. Vitamin D Levels and Risk of Retinopathy in Patients with Diabetes Mellitus. J Babol Univ Med Sci 2022; 24 (1) :189-198
URL: http://jbums.org/article-1-10802-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 24, Issue 1 (3-2022) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

The Journal of Babol University of Medical Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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