|
Vitamin D Levels and Risk of Retinopathy in Patients with Diabetes Mellitus
|
SA Rasoulinejad    , A Akbari * |
| 2.Department of Physiology, School of Veterinary Medicine, Shiraz University, Shiraz, I.R.Iran. , akbariabolfazl@gmail.com |
|
|
Abstract: (2605 Views) |
Background and Objective: Epidemiological data show a strong correlation between vitamin D deficiency and the incidence of diabetes mellitus. Many studies have reported hypovitaminosis D in patients with diabetic retinopathy, and it is possible that the deficiency of this vitamin plays a role in the pathogenesis of this diabetic complication. Therefore, the aim of this study is to investigate the serum levels of vitamin D in patients with diabetic retinopathy and its relationship with the prevalence of diabetic retinopathy.
Methods: In this review article, we searched Scopus, Google Scholar, and PubMed databases using the keywords vitamin D deficiency, serum vitamin D levels, vitamin D supplement, diabetes, and diabetic retinopathy. No time limit was considered for the search. Articles written in English were included in this study. Original and complete articles in English about vitamin D deficiency, diabetes and retinopathy were reviewed. Review articles and animal studies were excluded from this study. The data obtained from these findings were extracted and evaluated by two reviewers.
Findings: In this study, out of 52 studies found, 15 articles were reviewed according to the inclusion criteria. The results showed that vitamin D deficiency is very common in people with diabetes and diabetic retinopathy and there is a strong inverse relationship between vitamin D deficiency and diabetic retinopathy. In addition, the use of its supplements is also necessary to prevent the progression of diabetic retinopathy.
Conclusion: The results of this study suggest that the reduction of vitamin D serum levels is very common in patients with diabetic retinopathy and can be one of the risk factors for developing retinopathy. Its plasma level can have a high diagnostic value in order to prevent and control the onset of this complication. |
|
| Keywords: Vitamin D Deficiency, Vitamin D Serum Level, Vitamin D Supplement, Diabetes and Diabetic Retinopathy. |
|
|
Full-Text [PDF 337 kb]
(745 Downloads)
|
Type of Study: Review |
Subject:
Physiology
Received: 2022/05/26 | Accepted: 2022/06/27 | Published: 2022/07/9
|
|
|
|
|
|
|
| Send email to the article author |
|
|
