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Prevalence of Benign Prostatic Hyperplasia and Prostate Cancer in Patients Referred to Shahid Beheshti Hospital, Babol, In 2017-2018
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M Khazraee    , H Shafi , S Babazadeh , H Shirafkan , F Hoseini , Gh Kamrani * |
| , gh.kamrani@gmail.com |
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Abstract: (7 Views) |
Background and Objective: Benign prostatic hyperplasia is the most common disease of prostate which causes the serious urinary problems for men also prostate cancer is the most common cancer in men after lung cancer, and its incidence is increasing worldwide. Given that early diagnosis and treatment of prostate diseases can reduce malignancy and mortality, this study was conducted to investigate the frequency of benign hyperplasia and prostate cancer in Babol city.
Methods: In this cross-sectional study, the files of 573 patients who underwent prostate needle biopsy or open surgery at Shahid Beheshti Hospital in Babol during the years 2017-2022 were reviewed. The required information including age, place of residence, PSA level, histological diagnosis, and Gleason score in cases diagnosed with prostate cancer were collected and reviewed based on a checklist.
Findings: The mean age of the patients was 68.64±8.72 years and the mean PSA was 14.44±8.59 ng/ml. Of the 296 patients undergoing biopsy, 247 (83.4%) were diagnosed with benign prostatic hyperplasia and 49 (16.6%) with adenocarcinoma. Also, of the 277 patients undergoing open prostatectomy, 241 (87.0%) were diagnosed with benign hyperplasia and 36 (13.0%) with adenocarcinoma. The most common Gleason score was grade 2 with 38 cases (44.7%), followed by grade 3 with 33 cases (38.8%). Gleason score grade 4 with 9 cases (10.6%), grade 5 with 4 cases (4.7%), and grade 1 with 1 case (1.2%) were in the next ranks. The mean age and PSA in patients diagnosed with adenocarcinoma were significantly higher than in patients diagnosed with hyperplasia (p<0.001). There was no statistically significant difference in mean age and PSA between different Gleason grades.
Conclusion: The results showed that prostate cancer has a prevalence of 15% and that the incidence of prostate diseases increases with age. |
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| Keywords: Prostate, Adenocarcinoma, Benign prostatic hyperplasia, Biopsy, Open surgery. |
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Type of Study: Cross Sectional |
Subject:
Urology
Received: 2025/06/19 | Accepted: 2025/07/29
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