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:: Volume 21, Issue 1 (12-2019) ::
JBUMS 2019, 21(1): 135-139 Back to browse issues page
Serum αFP Level in Cord Blood of Full Term Neonates Born in Babol City
Y Zahedpasha , A Tamaddoni , M Ahmadpour-kacho , S Pourmoghtader
Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R.Iran , drtamaddoni@yahoo.com
Abstract:   (362 Views)
BACKGROUNDANDOBJECTIVE: Serum alpha-fetoprotein (αFP) level is considered as a diagnostic marker is higher than normal in many congenital tumors such as germ cell, hepatoblastoma, as well as liver and metabolic diseases in neonates. Normal neonates also have a higher level of alpha-fetoprotein than others, so it is important to diagnose this interference. In valid sources, the normal serum alpha-fetoprotein level in infants is related to advanced countries, which may vary in our country. Therefore, this study was conducted to determine the serum levels of alpha-fetoprotein in the umbilical cord blood of term neonates born in Babol and to compare them in two genders.
METHODS: This cross-sectional study was performed on 500 neonates (37-42 weeks) born in hospitals in Babol city where physical examination was normal. At birth, 5 ml of umbilical cord blood was taken and samples were sent to the lab for measurement of alpha-fetoprotein. Serum alpha-fetoprotein level was measured by ELISA method and was compared in two genders.
FINDINGS: Mean serum a FP levels was 76.57±35.25 ng/ml (range 2.3-160) and it was significantly higher in males (80.54±36.95 vs. 73.69±33.73 ng/ml) which was statistically significant (p=0.002).
CONCLUSION: The results of this study showed that the level of alpha-fetoprotein in neonates born in Babol is relatively high and also in males is more than females.
Keywords: Alfa-fetoprotein, Newborn, Umbilical Cord Blood
Full-Text [PDF 232 kb]   (91 Downloads)    
Type of Study: Research | Subject: Blood
Received: 2018/10/20 | Accepted: 2019/04/9 | Published: 2019/10/5
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Zahedpasha Y, Tamaddoni A, Ahmadpour-kacho M, Pourmoghtader S. Serum αFP Level in Cord Blood of Full Term Neonates Born in Babol City . JBUMS. 2019; 21 (1) :135-139
URL: http://jbums.org/article-1-8256-en.html

Volume 21, Issue 1 (12-2019) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

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