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Study of the effect of Lithium Chloride on memory and behaviour in rat
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A Arzi *   , M Moustofi |
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Abstract: (7895 Views) |
| Objective: In this study lithium chloride was used in order to find out its effect on memory and behavior of rats. Methods: In this experiment T-maze shaped apparatus was used. The animals used in this study were male rats with approximate weight of 120-150 g. The animals were randomly divided into two groups of fifty, one group received lithium chloride subcutaneously, where as the other group received normal saline as control. Two parameters: 1) Entrance direction of rats to each T-maze apparatus 2) Time taken by rats to reach the target box containing food, through T-maze shaped apparatus were studied. Findings: Statistical analysis of results indicates that the rat in the test group required a longer period of time to reach the target box, and also it had difficulty in choosing the box as compared with those in control group. Conclusion: On the basis of results, it might be indicated that lithium chloride has a negative effect on memory and behavior in rat. |
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| Keywords: Lithium chloride, Memory, Behaviour, Rat |
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Full-Text [PDF 888 kb]
(2071 Downloads)
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Type of Study: Research |
Subject:
Biochemical
Accepted: 2014/05/25 | Published: 2014/05/25
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