[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
Site Facilities::
Ethics::
peer-review::
Indexing::
Article types::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Journal DOI

AWT IMAGE

..
Copyright Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 
This Journal is licensed under a Creative Commons Attribution-NonCommercial 4.0
..
:: Volume 7, Issue 2 (4-2005) ::
J Babol Univ Med Sci. 2005; Volume 7 Back to browse issues page
Dosimetry, control and irradiation of rat cervical spinal cord
SR Mahdavi * , M Zabih Zadeh , AR Shirazi , H Gharaati
Abstract:   (6492 Views)
Background and Objective: In radiobiology, the most important physical radiation quantity to predict the effect of irradiation of a biological specimen is the absorbed dose to the tissue of interest. In this project an irradiation set up was designed and verification of set up and dosimetry procedure was performed to deliver a precise X-ray dose to the small field of rat cervical spinal cord. Methods: AAPM-TG61 (American association and physician in medicine radiation therapy committee task group 61) protocol was used for dose measurement and we tailored a rat like phantom from polyethylene for dosimetry verification. The ionization chamber in this study was a farmer type and the X-ray generator was an orthovoltage Siemens machine working at 200 KVp potential. Dosimetry was done in air and phantom. An special jig was also built to fix the animals during irradiation which could help the treatments to be reproducible. Simulation and portal films were obtained to verify the irradiation field. Findings: The average value of dose rate in specified geometries by measurement was 146.54 cGy/min (SD=0.109). While the dose determined by calculation was 95.145 cGy/min (SD=0.105), the comparison between these 2 methods shown a small discrepancy of 0.50% (P<0.001), which lies within the error limit of ±5.3% as mentioned by ICRU. Conclusion: Using protocol of AAPM TG-61 can provide an accurate dosimetry with minimum ambiguity. Application of appropriate correction factors and protocols can increase the accuracy and decrease the irradiation errors in radiobiological studies.
Keywords: X-ray dosimetry, Radiobiology, Rat cervical spinal cord irradiation, Rat phantom, Jig
Full-Text [PDF 585 kb]   (2070 Downloads)    
Type of Study: Research | Subject: Biochemical
Accepted: 2014/05/31 | Published: 2014/05/31


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mahdavi S, Zabih Zadeh M, Shirazi A, Gharaati H. Dosimetry, control and irradiation of rat cervical spinal cord. J Babol Univ Med Sci 2005; 7 (2) :7-13
URL: http://jbums.org/article-1-2630-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 7, Issue 2 (4-2005) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

The Journal of Babol University of Medical Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Persian site map - English site map - Created in 0.05 seconds with 43 queries by YEKTAWEB 4657