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The Association between Early Repolarization Pattern and Coronary Artery Disease Based on Coronary Angiography
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E Chogan    , S Abrotan , H Shirafkan , K Amin , M Hedayati * |
| 2.Clinical Research Development Unite of Rouhani Hospital, Babol University of Medical Sciences, Babol, I.R.Iran. , drmohammad.hedayati@yahoo.com |
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Abstract: (124 Views) |
Background and Objective: Coronary artery disease is considered as the most important disease among cardiovascular diseases. Recently, evidence has emerged suggesting an association between early repolarization and coronary artery disease. Therefore, the present study was conducted to investigate the association between electrocardiographic early repolarization pattern and coronary artery disease based on coronary angiography in patients who underwent angiography at Ayatollah Rouhani Hospital in Babol, northern Iran.
Methods: This cross-sectional study was conducted on all patients who underwent angiography in 2019 at Rouhani Hospital in Babol. The association between early repolarization and demographic variables as well as laboratory tests of the patients was evaluated. Subsequently, patients were divided into high-risk, moderate-risk, and low-risk groups based on the Framingham criteria, and the association between early repolarization and coronary artery disease was investigated and compared in each group.
Findings: 1,351 patients were evaluated in this study. Overall, the early repolarization pattern was observed to be more common in men (190 [23.5%] vs. 102 [18.8%]; p<0.01). According to the Framingham criteria, 648 patients had low risk, 386 had moderate risk, and 317 had high risk of coronary artery disease. Among patients with low or moderate risk according to the Framingham criteria, those with an early repolarization pattern were more likely to have >50% coronary artery stenosis.
Conclusion: The results of the study demonstrated that even among patients with low or moderate risk according to the Framingham criteria, the presence of early repolarization, in addition to traditional risk factors, predicts a higher rate of coronary artery disease. Furthermore, these patients are at a higher risk for multivessel involvement. |
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| Keywords: Electrocardiography, Angiography, Coronary Artery Disease, Early Repolarization. |
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Full-Text [PDF 300 kb]
(31 Downloads)
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Type of Study: Cross Sectional |
Subject:
Cardiovascular
Received: 2025/10/5 | Accepted: 2025/11/19 | Published: 2026/05/2
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