|
The Effect of Aqueous Extract of Mentha Longifolia on the Clinical and Paraclinical Status of Patients with COVID-19
|
S Jelodar    , AS Hosseini , M Kamalinejad , F Babamahmoodi , M Moosazadeh , H Majidi , M Yousofpour * |
| 1.Department of Persian Medicine, School of Persian Medicine, Mazandaran University of Medical Sciences, Sari, I.R.Iran. , m.yousofpoor@yahoo.com |
|
|
Abstract: (918 Views) |
Background and Objective: Following the outbreak of the COVID-19 pandemic, numerous industrial and traditional medicines have been proposed and used to treat this disease. Given the lack of standard treatment and effective medicine for COVID-19 and the effectiveness of Mentha longifolia on pulmonary diseases, this study was designed and conducted to determine the effect of aqueous extract of Mentha longifolia on the clinical and paraclinical status of patients with COVID-19.
Methods: This clinical trial was conducted on 60 patients with COVID-19 hospitalized at Razi Hospital in Ghaemshahr (Mazandaran) in 2021. Patients were selected through purposive sampling. 30 people were randomly assigned into control group with standard treatment, and 30 people in the intervention group who received Mentha longifolia extract in the form of a nasal spray 2 puffs every 12 hours in addition to standard treatment. The main clinical variables included fever, cough, chest pain, shortness of breath, fatigue, and chills. Chest radiography was interpreted by a radiologist. The clinical definition of complete recovery included the absence of fever for two days, respiratory rate less than or equal to 15-20 breaths per minute, oxygen saturation greater than 95%, no cough or mild dry cough, and the clinical definition of partial recovery included body temperature less than or equal to 37.9 ºC orally or 37.2 ºC axillary, respiratory rate 20-24 breaths per minute, oxygen saturation between 93-95%, no cough or mild dry cough.
Findings: The two groups did not differ significantly in terms of gender, age, BMI, and underlying disease. The mean length of stay in the intervention group was 2.5 days shorter than in the control group (12.1±6.8 days in the control group and 9.6±7.1 days in the intervention group) (p=0.171). The number of deaths was not statistically significant but was clinically significant (6.7% in the intervention group and 16.7% in the control group). 26.7% of the control group and 50% of the intervention group had a complete recovery within the first 7 days after discharge. 30% of the control group still did not feel better 15 days after discharge, while this rate was zero in the intervention group.
Conclusion: The results of the study showed that aqueous extract of Mentha longifolia reduced the length of hospital stay and improved symptoms in patients with COVID-19.
|
|
| Keywords: Coronavirus, COVID-19, Mentha Longifolia, Persian Medicine. |
|
|
Full-Text [PDF 298 kb]
(164 Downloads)
|
Type of Study: Research |
Subject:
Traditional Medicine
Received: 2023/11/3 | Accepted: 2024/03/13 | Published: 2025/04/6
|
|
|
|
|
|
|
| Send email to the article author |
|
|
