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:: Volume 26 - ::
J Babol Univ Med Sci. 2024; Volume 26 Back to browse issues page
Evaluation of Epithelial Cells of Oral Mucosae in Patients with Fixed Orthodontic Appliance
A Shiva , F Moaddabi , S Arab , M Khatami , M Zamanzadeh , M Koochek Dezfouli , A Hossein Nataj , P Namdar *
5.Department of Orthodontics, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, I.R.Iran. , dds.pnamdar@gmail.com
Abstract:   (922 Views)
Background and Objective: Orthodontic appliances are usually in contact with the oral mucosa for a long time due to the length of the long-term treatment and are associated with problems due to the continuous contact and friction created. This study was conducted to investigate the epithelial cells of the mucosa of patients with fixed orthodontic appliances.
Methods: In this cross-sectional study, smears were collected from three separate areas in 150 patients referred to the dental clinic of Mazandaran University: Area A (slide A): oral mucosa exposed to friction caused by orthodontic brackets, area B (slide B): oral mucosa exposed to friction with the tube on the orthodontic tape and Area C (slide C): oral mucosa without friction, i.e., the lower area of the oral cavity (control area). For histomorphometric analysis, each slide was evaluated with Papanicolaou staining using a light microscope, and the nuclear area (NA), cytoplasmic area (CA), and the ratio of nuclear area to cytoplasmic area (NA/CA) were recorded in square micrometers.
Findings: The mean NA was 65.66±22.11, CA was 717.37±1846.53, and NA/CA was 0.037±0.010 square meters. The difference in NA and CA between slides was significant )p<0.001) (slide A
Conclusion: The findings of the study indicate that fixed orthodontic treatment has a significant impact on the nuclear and cytoplasmic area of affected areas compared to non-affected areas. Only some degree of inflammation may be seen in the areas exposed to the orthodontic appliance.
Keywords: Epithelial Cells, Oral Mucosa, Fixed Orthodontics, Histomorphometry, Papanicolaou Staining, Orthodontic Appliances, Cytotoxicity.
Full-Text [PDF 327 kb]   (181 Downloads)    
Type of Study: Research | Subject: Dentistry (Orthodontics)
Received: 2023/06/2 | Accepted: 2023/09/17 | Published: 2024/08/21
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Shiva A, Moaddabi F, Arab S, Khatami M, Zamanzadeh M, Koochek Dezfouli M, et al . Evaluation of Epithelial Cells of Oral Mucosae in Patients with Fixed Orthodontic Appliance. J Babol Univ Med Sci 2024; 26
URL: http://jbums.org/article-1-11425-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 26 - Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

The Journal of Babol University of Medical Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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