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JBUMS 2014, 16 - : 65-74 Back to browse issues page
Orthopedic (Osteoarticular) Manifestations of Brucellosis
N. Janmohammadi (MD) *, M.R. Hasanjani Roushan (MD)
Abstract:   (34444 Views)


BACKGROUND AND OBJECTIVE: Brucellosis such as tuberculosis is a multisystem chronic inflammatory and infectious granulomatous disease with various and deceptive manifestations that involves bone, joint and related structures. Orthopedic (osteoarticular) manifestations are the most common and various localized forms of brucellosis which were discussed in this study.


METHODS: For preparation of this manuscript by using Mesh keywords about osteoarticular manifestations of tuberculosis, 107 papers published in Scopus, Google Scholar, Pubmed and Elsevier during 1974-2013 and textbooks of Campbell's operative orthopedics, Tachdjian's pediatric orthopedics, Principles and Practice of Infectious Diseases and Feigin and Cherry Pediatric infectious Diseases were used.


FINDINGS: The axial skeleton (vertebrae) is the most common site of involvement with a frequency ranging from 2% to 53%. Half of patients suffering from brucellosis manifest with back pain. Spondylitis or osteomylitis of vertebra with frequency of 2 to 60% due to causing neurological complication is the dangerous form of brucellosis and the spondylodiscitis is the rigorous one because of the possibility of neurological deficit and death. In the extremities, brucellosis presents as enthesopathy, myalgia, bursitis, myositis, arthralgia, arthritis, osteomyelitis, tendonitis and tenosynovitis. Brucellosis may involve artificial knee and hip joints. Brucellar arthritis and osteomyelitis concomitant with extra articular metallic devices were also reported.


CONCLUSION: Brucellosis manifests with various musculoskeletal (orthopedics) manifestations. In confronting patients with musculoskeletal malaise sustaining a high index of suspicion is essential particularly in risk individuals and in patients living in endemic areas for early diagnosis and to prevent mistake and its unpleasant outcomes. Diagnosis of osteoarticular brucellosis is based on clinical findings, and various diagnostic measures. Diagnosis and appropriate treatment of these patients necessitates friendly cooperation between orthopedist, neurosurgeon and infectious diseases specialist.




Keywords: Brucellosis, Manifestations, Orthopedics, Osteoarticular.
Full-Text [PDF 374 kb]   (4983 Downloads)    
Type of Study: Research | Subject: Biochemical
Received: 2013/01/27 | Accepted: 2013/05/1 | Published: 2014/08/9

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Janmohammadi (MD) N, Hasanjani Roushan (MD) M. Orthopedic (Osteoarticular) Manifestations of Brucellosis . JBUMS. 2014; 16 (S1) :65-74
URL: http://jbums.org/article-1-4948-en.html

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Volume 16 - Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

The Journal of Babol University of Medical Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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