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:: Volume 13, Issue 2 (3-2011) ::
JBUMS 2011, 13(2): 7-11 Back to browse issues page
Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
M Alvandipour *, P Tayebi, R Alizadeh Navaie, H Khodabakhshi
Abstract:   (21278 Views)
BACKGROUND AND OBJECTIVE: Mastalgia is a common painful complaint in women. Several different therapeutic components are used for mastalgia treatment. Vitamin E and Evening Primrose oil (EPO) are some of these components that used for cyclic mastalgia. This study was designed to compare EPO and Vitamin E in treatment of cyclic mastalgia and to find the best treatment for it.
METHODS: This study was done as a double blind clinical trial on 100 women suffered cyclic mastalgia. Patients was divided in 4 study groups with 25 patients in each group, included: 1. Evening Primrose oil 2 gr/day, 2. Vitamin E 400 unit daily, 3. Evening Primrose oil and Vitamin E, 4. Placebo. The MC Gill Questionnaires was used for patients pain evaluation before study and 1 and 6 months after intervention.
FINDINGS: The mean of MC Gill score in Primrose oil group before investigation was 6.23±1.004 and was decreased to 2.68±1.002 six months after primrose oil consumption. Also in Vitamin E group this mount was decreased from 6.04±1.342 to 3.06±1.482. Overally the mean of MC Gill score in each of three therapeutic group was decreased after the intervention against placebo group (p=0.000). Also the difference of MC Gill score between these three therapeutic groups hasn any significant change.
CONCLUSION: The results of present study show that Vitamin E and Primrose oil have a same therapeutic effect in the treatment of cyclic mastalgia and these drugs can be used as a suitable therapeutic alternative in the patient with cyclic mastalgia.
Keywords: Cyclic mastalgia, Vitamin E, Primrose oil
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Type of Study: Research | Subject: Biochemical
Accepted: 2014/06/7 | Published: 2014/06/7


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Alvandipour M, Tayebi P, Alizadeh Navaie R, Khodabakhshi H. Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia. JBUMS. 2011; 13 (2) :7-11
URL: http://jbums.org/article-1-3734-en.html


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Volume 13, Issue 2 (3-2011) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

The Journal of Babol University of Medical Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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