[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
Site Facilities::
Ethics::
peer-review::
Indexing::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Journal DOI

AWT IMAGE

..
Copyright Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 
This Journal is licensed under a Creative Commons Attribution-NonCommercial 4.0
..
:: Volume 25, Issue 1 (3-2023) ::
J Babol Univ Med Sci. 2023; Volume 25 Back to browse issues page
Association of BMI and Age with Gleason Score and PSA in Patients with Prostate Cancer
SA Mazloumi , E Moudi * , H Shafi , H Gholinia
2.Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol I.R.Iran. , emadmoudi@gmail.com
Abstract:   (176 Views)
Background and Objective: Obesity has produced conflicting results on various indices of prostate cancer diagnosis. Since the effect of body mass index (BMI) on Gleason score and prostate specific antigen (PSA) as well as the overall classified risk of prostate cancer results is important, the present study was conducted to investigate the association of BMI and age with Gleason score and PSA in Patients with prostate cancer.
Methods: In this cross-sectional study, 310 prostate cancer patients referred to the affiliated hospitals of Babol University of Medical Sciences from 2011 to 2021 were evaluated in terms of age, height, weight, PSA and Gleason score. Based on BMI, the patients were divided into three groups: obese (BMI≥30), overweight (BMI=25-30) and normal weight (BMI<25) and according to the Gleason score into three low grades (G/S<7), medium grade (G/S=7), high grade (G/S>7) and were divided into three categories based on PSA: 4-10, 10-20 and more than 20. Then, the association of BMI and age with Gleason score and PSA was investigated.
Findings: The mean BMI of the patients was 26.3±3.77 kg/m2. The mean PSA was 35.72±8.5 ng/dL and the mean Gleason score was 7.1±1.11. The mean Gleason score increased with increasing age (p<0.001, r=0.307). A higher Gleason score had a significant relationship with PSA increase (p<0.001, r=0.485). BMI had no significant association with Gleason score (r=0.072, p=0.102). PSA decreased slightly with increasing BMI (p=0.006, r=0.157).
Conclusion: The results of the study showed that increasing age is associated with a higher Gleason score. But the increase in BMI is not related to increased risk of prostate cancer and increased Gleason score.
Keywords: Body Mass Index, Age, Gleason Score, Prostate Specific Antigen.
Full-Text [PDF 300 kb]   (64 Downloads)    
Type of Study: Research | Subject: Urology
Received: 2023/08/25 | Accepted: 2023/11/8 | Published: 2023/11/20
Send email to the article author



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mazloumi S, Moudi E, Shafi H, Gholinia H. Association of BMI and Age with Gleason Score and PSA in Patients with Prostate Cancer. J Babol Univ Med Sci 2023; 25 (1) :455-462
URL: http://jbums.org/article-1-11663-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 25, Issue 1 (3-2023) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

The Journal of Babol University of Medical Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Persian site map - English site map - Created in 0.05 seconds with 43 queries by YEKTAWEB 4639