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The Effectiveness Treatment with Chamomile on Menstrual Function, Dysmenorrhea and Premenstrual Syndrome in Women with Polycystic Ovary: Randomized Clinical Trial
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M Afiat    , E Jalaly , H Lashgari Kalat , N Khorsand , A Akbari Lor , M Ghazanfarpour * |
| 6.Reproductive Health, Family and Population Research Center, Kerman University of Medical Sciences, Kerman, I.R.Iran. , Masumeh.Ghazanfarpour@yahoo.com |
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Abstract: (249 Views) |
Background and Objective: Despite previous descriptive studies found a significant association between dysmenorrhea and premenstrual syndrome and polycystic ovary syndrome. No clinical trial has examined the effectiveness of treatment on these two symptoms. The aim of this study was to evaluate the effect of chamomile on dysmenorrhea and premenstrual syndrome in patients with polycystic ovary syndrome.
Methods: This randomized clinical trial performed on 70 patients polycystic ovary syndrome diagnosed as per the Rotterdam criteria and affected referring to the specialized clinics of Mashhad hospitals. Patients were allocated randomly to intervention and control groups. The intervention group received two 500 mg chamomile capsules daily for three months, while the controls received two placebo capsules daily for the same period. Outcomes considered in the current study were premenstrual syndrome, dysmenorrhea, oligomenorrhea, body mass index. Demographic questionnaire, Visual analogue scale and premenstrual syndrome questionnaire were used in current research.
Findings: The average age of the patients in the intervention group was 25.43±5.58 and in the placebo group was 28.06±5.71. The rate of improvement in women with premenstrual syndrome (16.6%), dysmenorrhea (50%) and oligomenorrhea (26.7%) was higher in chamomile group compared to placebo. However, no statistically significant difference was observed between the chamomile and placebo groups regarding the mentioned parameters. In the before after comparison of body mass index (28.25±98.4) and treatment (17.95±25.4) with chamomile, no significant difference was observed (p=0.24). Also, significant difference between the chamomile group (25.17±4.95) and control group (25.57±6.7) in terms of body mass index (BMI) were not observed.
Conclusion: Chamomile improved oligomenorrhea in patients affected with polycystic ovary syndrome and was also effective in treating dysmenorrhea and premenstrual syndrome in these individuals. Therefore, chamomile can be used as a simple, low-cost and multi-purpose measure in the treatment of patients with polycystic ovary syndrome. |
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| Keywords: Matricaria, Dysmenorrhea, Premenstrual Syndrome, Polycystic Ovary Syndrome, Testosterone, Oligomenorrhea. |
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Type of Study: Interventional |
Subject:
Midwifery
Received: 2023/03/4 | Accepted: 2023/08/13
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