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Comparison the Effects of Intravenous Lidocaine versus Lidocaine Spray after LMA Insertion
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H Sorayae    , Sh Seyfi * , P Amri Maleh , H Gholinia , A Ataie |
| 2.Clinical Research Development Unite of Rouhani Hospital, Babol University of Medical Sciences, Babol, I.R.Iran. , sh.seifi@mubabol.ac.ir |
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Abstract: (59 Views) |
Background and Objective: Laryngeal mask airway (LMA) is frequently used in anesthesia of short-term surgeries. Pretreatment with intravenous (IV) lidocaine leads to improve patient’s condition during placement and removal of LMA. Considering the probable adverse effects of IV lidocaine, the primary object of this study was to compare spray form of lidocaine versus IV lidocaine in blood pressure changes following LMA insertion. In secondary objectives pulse rate, the intensity of sore throat, cough, and other complications including laryngospasm, nausea, vomiting, and seizure were evaluated.
Methods: This randomized double-blind clinical trial was conducted on 120 patients aged 18-65 years with an indication for short- term elective eye surgery. They were randomly divided into two groups (n=60 in each group). The first group received 1.5 mg/kg IV lidocaine 10% and the second group received 5 sprays of 10% lidocaine in the posterior part of the pharynx. In both groups, blood pressure by mercury nanometer, heart rate by heart rate monitoring system, severity of sore throat by visual analog scale (VAS) criteria, and severity of cough ( mild, moderate, and severe) were recorded at different time points.
Findings: This study included 71 (65.8%) men and 41 (42.2%) female. No remarkable clinically change in blood pressure was observed in both groups. The intensity of sore throat was significantly reduced at 2 and 3 hours after consciousness in lidocaine spray 0.51±1.33 and 0.41±1.07 compared with IV lidocaine group 1.15±2.02 and 1.08±1.9, respectively (p<0.05). About heart rate, cough severity, and laryngospasm no significant difference were observed in both groups. In addition, we did not find any case with nausea, vomiting, and seizure.
Conclusion: Lidocaine spray can be proposed for reducing the intensity of sore throat caused by LMA insertion. |
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| Keywords: Hemodynamic Changes, Lidocaine Spray, Intravenous Lidocaine, Laryngeal Mask Airway, Sore Throat, Cough. |
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Type of Study: Interventional |
Subject:
Anesthesia
Received: 2023/05/8 | Accepted: 2023/07/26
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