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:: Volume 13, Issue 1 (2-2011) ::
JBUMS 2011, 13(1): 82-89 Back to browse issues page
Local Application of Antibiotics in Periodontal Pockets
B Amoian , AA Moghadamnia, B Vadiati, J Mehrani
Abstract:   (4621 Views)
Given the fact that, periodontal disease is a disease with an infective agent, treatment by using antibiotics with scaling and root planing (SRP) has been considered as an adjunctive therapy. According to disadvantages of systemic antibiotic therapy such as: resistance, fluctuations in concentration, need for cooperation and side effects, local drug delivery systems in the form of irrigants or forms of drug releasing agents, seems to be a suitable substitute. Because periodontal diseases are often limited to several teeth. A local delivery device consists of a drug reservoir and a limiting element that controls the rate of medicament release. The goal is to maintain effective concentrations of chemotherapeutic agents at the site of action for long periods, despite drug loss from cervicular fluid clearance. Current data suggest that local delivery of antimicrobials into a periodontal pocket can improve periodontal health. It can be concluded that the adjunctive use of local drug delivery may provide a defined, but limited, beneficial response.
Keywords: Chronic periodontitis, Local drug delivery systems, Antibiotic, Antiseptic
Full-Text [PDF 201 kb]   (695 Downloads)    
Type of Study: Research | Subject: Biochemical
Accepted: 2014/06/7 | Published: 2014/06/7

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Amoian B, Moghadamnia A, Vadiati B, Mehrani J. Local Application of Antibiotics in Periodontal Pockets. JBUMS. 2011; 13 (1) :82-89
URL: http://jbums.org/article-1-3724-en.html

Volume 13, Issue 1 (2-2011) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

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