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:: Volume 9, Issue 4 (10-2007) ::
JBUMS 2007, 9(4): 23-28 Back to browse issues page
SALIVARY ALKALINE PHOSPHATASE ACTIVITY AND INORGANIC PHOSPHORUS CONCENTRATION IN CHILDREN WITH DIFFERENT DENTAL CARIES
S Mahjoub , M Ghasempour,, I Mohammadi
Abstract:   (5535 Views)
BACKGROUND AND OBJECTIVE: Dental caries is the most common dental disease in children. Alkaline phosphatase (ALP) activity and inorganic phosphorus concentration in saliva may be related to the susceptibility to dental caries.METHODS: In this case-control study, one hundred children in the age group of 4 – 6 years were divided into 3 groups: group one, 30 caries– free children with dfs <1, group two, 33 children with 5< dfs ≤10 and group three, 37 children with dfs> 10. The unstimulated mixed salivary sample was collected from each child. After centrifuge, supernatants were separated and measurements of salivary ALP activity and inorganic phosphorus concentration were performed by using colorimetric techniques. Data were analyzed by SPSS software and student t-test. FINDINGS: Mean of dfs in groups 1, 2 and 3 were 0.36, 7.12 and 16.32, respectively. Mean values of ALP activity in group 2 (16.9 IU/L) and group 3 (18.3 IU/L) were significantly higher than group 1 (5.4 IU/L) (p<0.05). In addition, mean values of inorganic phosphorus in group 2 (31.1mg/dl) and group 3 (29.3mg/dl) were significantly higher than group 1 (16.2mg/dl) (p< 0.05).CONCLUSION: Our results revealed that ALP activity and inorganic phosphorus concentration had a direct relationship with the increase in caries rates. But this relationship was not seen between moderate and severe caries.
Keywords: Alkaline phosphatase, Inorganic phosphorus, Dental caries, Saliva
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Type of Study: Research | Subject: Biochemical
Accepted: 2014/06/2 | Published: 2014/06/2


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Mahjoub S, Ghasempour, M, Mohammadi I. SALIVARY ALKALINE PHOSPHATASE ACTIVITY AND INORGANIC PHOSPHORUS CONCENTRATION IN CHILDREN WITH DIFFERENT DENTAL CARIES. JBUMS. 2007; 9 (4) :23-28
URL: http://jbums.org/article-1-2518-en.html


Volume 9, Issue 4 (10-2007) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

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