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A Comparison between the Effects of Hyaluronic Acid and Platelet-Rich Plasma on Temporomandibular Joint Pain and Clicking
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S Radhi Thamer    , A Ryhan Diajil * |
| 1.Department of Oral Diagnosis Sciences, College of Dentistry, Baghdad University, Baghdad, Iraq. , ameenaryhan3d@yahoo.com |
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Abstract: (81 Views) |
Background and Objective: Patients with temporomandibular joint internal derangement (TMJ-ID) present with joint sounds, local or radiating pain and issues regarding the function of the mandible. The aim of this study is to investigate the therapeutic benefits of intra-articular injection of platelet-rich plasma (PRP) and hyaluronic acid (HA) on pain and clicking in TMJ-ID patients.
Methods: In this cross-sectional study, 52 patients with TMJ-ID were randomly selected and divided into two groups. Thirty patients were injected with HA for three sessions 10 days apart, and 22 patients were injected with PRP for three sessions 14 days apart. Joint pain and clicking was assessed through 5 follow-up sessions. Pain was assessed using a numeric pain rating scale ranging from 0 to 10. The clicking sound was assessed using a rating system of (0-3).
Findings: The mean age of the patients was 28.6±9.1 years. After treatment, significant improvement in pain and clicking was observed in both groups. HA (0.9±2.6, MR1=2.26) showed a lower mean value in pain and clicking compared to PRP (1.8±3.5, MR1=9.26), but did not reach a statistically significant level.
Conclusion: The results of the study showed positive therapeutic effects for both HA and PRP in terms of reducing joint pain and clicking sounds. |
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| Keywords: Temporomandibular Disorder, Minimally Invasive Procedure, Randomized Clinical Trial, Intraarticular Injection. |
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Type of Study: Research |
Subject:
Restorative Dentistry
Received: 2024/04/3 | Accepted: 2024/07/2
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