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:: Volume 20, Issue 3 (3-2018) ::
JBUMS 2018, 20(3): 29-35 Back to browse issues page
The Relationship between Serum Zinc Level and Liver Elastrography Using Fibroscan in Non-Alcoholic Fatty Liver Patients
E Hajiani , A Parsi , K Erfanian Taghvaie , M Morvaridi
, dr_abazar_parsi@yahoo.com
Abstract:   (938 Views)
BACKGROUND AND OBJECTIVE: Zinc is one of the essential elements for many vital functions of the body, including regulation of gene expression, anti-inflammatory and antioxidant activity, protein and nucleic acids metabolism. Since, many people develop advanced liver disease, including liver cirrhosis, they have zinc deficiency. The aim of this study was to investigate the relationship between liver stiffness and serum zinc levels in patients with non-alcoholic fatty liver disease.
METHODS: This cross-sectional study was performed on 40 non-alcoholic fatty liver disease Patients referring to Imam Khomeini Hospital in Ahvaz in 1395. Serum zinc levels and liver Stiffness (based on METAVIR scale) were measured by fibroscan, and Age, sex, serum zinc level and liver fibroscan were recorded. Serum zinc level at different ages and scores of Liver stiffness was compared and analyzed.
FINDINGS: This study was conducted on 40 patients with non-alcoholic fatty liver disease. The number of men was 26 patients (65%). Mean age of patients was 45.077±9.4 years, mean serum zinc level was 81.4±8.1 and mean liver stiffness was 6.5±2.1 kPa. Serum zinc level had a reverse and strong correlation with liver stiffness (p=0.0001, r=0.9). Also, with age increasing, liver stiffness increased (p=0.01, r=0.5) and serum zinc level decreased (p=0.01, r=0.5).
CONCLUSION: According to findings of the present study, the serum zinc level significantly decreased with fibrosis progression in patients with non-alcoholic fatty liver.
Keywords: Non-Alcoholic Fatty Liver, Zinc, Elasticity Imaging Techniques.
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Type of Study: Cross Sectional | Subject: e
Received: 2017/08/6 | Accepted: 2018/03/5 | Published: 2018/03/17
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Hajiani E, Parsi A, Erfanian Taghvaie K, Morvaridi M. The Relationship between Serum Zinc Level and Liver Elastrography Using Fibroscan in Non-Alcoholic Fatty Liver Patients. JBUMS. 2018; 20 (3) :29-35
URL: http://jbums.org/article-1-7036-en.html


Volume 20, Issue 3 (3-2018) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

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