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JBUMS 2014, 16 - : 85-94 Back to browse issues page
The Effects of Parenteral Fish Oil Administration in ICU Patients
E. Sharifi (MSc), S. Saraf-Bank (MSc), L. Azadbakht (PhD) *
Abstract:   (9489 Views)

BACKGROUND AND OBJECTIVE: Malnutrition is a prevalent problem among ICU patients. After 3-4 days of hospitalization, many patients enter in a negative energy balance. Early nutritional support is an effective way to improve clinical outcomes in these patients. The type of fat emulsion in parentral nutrition is effective on immune system function. There are several evidences emphasized on the beneficial effects of fish oil based lipid emulsions. Regarding to parenteral nutrition importance and the type of lipid emulsion, the aim of this study was to review the effects of omega 3 administration among ICU patients.


METHODS: We searched key words including omega 3, fish oil, and parenteral nutrition in PubMed search engine. 354 papers were obtained. After limiting to title/abstract and human studies, finally 66 papers about sepsis, trauma and surgery was selected.


FINDINGS: Fish oil consumption change the Arachidonic acid metabolism. Most studies conducted on septic and operated patients declared that fish oil consumption can improve clinical outcomes and reduced the inflammatory markers. Furthermore several studies confirmed the beneficial effects of fish oil consumption on length of hospital stay and antibiotic requirement in multiple trauma or head injured patients.


CONCLUSION: It seems that fish oil administration in ICU patients is associated with reduction in inflammatory levels, shorter hospitalization period and improvement of other clinical outcomes contributed to inflammation.



Keywords: Fish oil, Parenteral nutrition, ICU, Inflammation, Sepsis, Craniocerebral trauma, Digestive system surgical procedure.
Full-Text [PDF 500 kb]   (1519 Downloads)    
Type of Study: Research | Subject: Biochemical
Received: 2013/01/30 | Accepted: 2013/07/10 | Published: 2014/08/9

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Sharifi (MSc) E, Saraf-Bank (MSc) S, Azadbakht (PhD) L. The Effects of Parenteral Fish Oil Administration in ICU Patients. JBUMS. 2014; 16 (S1) :85-94
URL: http://jbums.org/article-1-4950-en.html

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