BACKGROUND AND OBJECTIVE: Organophosphates are designed to eliminate weeds, rodents, and harmful organisms and to repel insects and fungi. The greatest impact of organophosphates is on the immune system and reproductive organ. The present study was conducted to investigate the effect of organophosphates on fertility.

METHODS: In this study, the articles on organophosphate pesticides and their adverse effects on body tissues and organs, such as reproductive system and different articles about agricultural pesticides and infertility were extracted from NCBI database. The studies conducted about the effect of organophosphate pesticides on the quality of sperm and ovum, greenhouse role of pesticides, and their effect were used.

FINDINGS: Genetic toxicity, endocrinology disorder, and immune toxicities are the long-term signs and symptoms of organophosphates which depend on the type and amount of contact with them. Skin reaction, respiratory system stimulation, allergic responses, and neural problems are some of their complications. Biochemical process and material transfer in cells may be disturbed in contact with it. There is also testicular tissue damage, ovarian failure, and hormonal disorder associated with a variety of pesticides.