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Comparing the Effect of Hysterectomy with and without Salpingectomy on Preserving Ovarian Reserve
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Sh Yazdani    , R Mehraein , M Mohammad Pour , S Khafri , A Ghanbarpour * |
| 1.Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R.Iran. , dr_ghanbarpour@yahoo.com |
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Abstract: (40 Views) |
Background and Objective: Ovarian cancer has the highest mortality rate among all types of female cancer. Many malignancies currently classified as ovarian cancer may arise in the tubal epithelium. Therefore, prophylactic removal of the tubes may result in a reduced risk of malignancy. Salpingectomy appears to reduce ovarian reserve, although some studies have suggested otherwise. Given these conflicting results, we decided to conduct a study to investigate the effect of prophylactic salpingectomy on ovarian reserve.
Methods: This single-blind clinical trial study was conducted on 53 women of reproductive age <45 years with FSH <10 who were candidates for abdominal hysterectomy with ovarian preservation and referred to Rouhani Hospital in Babol between 2010 and 2011. One group of patients underwent abdominal hysterectomy with ovarian preservation and simultaneous salpingectomy (27 patients), and the other group underwent no salpingectomy (26 patients). Antral follicle volume and volume were measured by ultrasound and FSH and AMH levels were measured in the laboratory before and three months after surgery and compared.
Findings: According to our results, FSH significantly increased three months after surgery compared to before surgery in all patients and in both groups (p<0.001), but AMH, antral follicle count, and ovarian volume significantly decreased (p<0.001). There was no statistically significant difference between the two study groups in terms of mean FSH, AMH, ovarian follicle count, and ovarian volume three months after surgery (p-values, 0.071, 0.898, 0.957, and 0.163, respectively).
Conclusion: Our results showed that a statistically significant decrease in ovarian function was observed in both groups after surgery and was not related to salpingectomy. Therefore, prophylactic salpingectomy can be recommended to prevent ovarian cancer. |
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| Keywords: Hysterectomy, Salpingectomy, Ovarian Reserve. |
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Type of Study: Interventional |
Subject:
Obstetrics and Gynecology
Received: 2024/11/4 | Accepted: 2025/02/2
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