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Evaluation of Treatment Outcome of Myocardial Infarction with Thrombolytic and Angioplasty
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MS Ramezani    , S Pouraria , F Jalali , K Amin , H Gholinia , I Jafaripour * |
| 1.Clinical Research Development Unite of Rouhani Hospital, Babol University of Medical Sciences, Babol, I.R.Iran. , iraj595@yahoo.com |
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Abstract: (142 Views) |
Background and Objective: The standard treatment in patients with acute myocardial infarctus is to restore blood flow in the closed vessels, which is possible through angioplasty and therapeutic thrombolysis. But even in developed countries, some patients still do not receive coronary intervention treatment due to difficulties in accessing Primary Percutaneous Coronary Intervention (PCI) centers and unprepared angiography, which can lead to unwanted consequences. So the study was conducted to compare the results of primary angioplastic therapy and thrombolysis therapy.
Methods: This comprehensive study was conducted on 291 ST Elevation Myocardial Infarction (STEMI) patients who visited clinics covered by the Babol University of Medical Sciences. Patients under primary PCI (213 people) or thrombolytic therapy (78 people) were reviewed and compared in terms of demographic and clinical data, mortality rate, major cardiovascular events, need for re-PCI, need to re-inject.
Findings: The mean age of patients was 60.55±11.90 years and 72% of patients were male. The recurrent PCI was on the same scale in the primary PCI group, 11% (6 cases) and in the thrombolytic group, 23% (7 cases). Recurrence due to chest pain and shortness of breath was 30% in the primary PCI group (59 people) and 39% (38 people) in the thrombolytic therapeutic group. The likelihood of death in patients treated with thrombolysis was 1.38 compared to PCI (p=0.56, OR=1.38), which was not significant. The increase in EF also significantly decreased the likelihood of death (p=0.001, OR=14.64). EF and FC had no statistical differences between the two groups. The average duration between pain start and hospital visit and thrombolysis was 276±147 and 33±5 minutes and in the PCI group 323±169 and 37±6 minutes. The likelihood of recurrence of MI in patients treated with thrombolysis was 1.53 compared to primary PCI (p=0.54, OR=1.53), which was not significant.
Conclusion: Based on the results of the study in both groups, if the patient went to the hospital shortly after the start of the pain, the treatment results were better. The rate of re-MI and MI on the same track did not differ in the two groups. |
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| Keywords: Percutaneous Coronary Intervention, Thrombolytic Therapy, Myocardial Infarction. |
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Type of Study: Research |
Subject:
Cardiovascular
Received: 2023/07/23 | Accepted: 2023/10/16
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