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                                  Impact of Pretreatment of Dentin with Omega-9 on Microtensile Bond Strength of Fifth-Generation Dentine Adhesive at Different Times
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								    Sh Kermany        ,  F Moktarpour        ,  S Seyedmajidi        ,   M Ghasempour *         | 
								
								
								  | 3.Oral Health Research Center, Health Research Institute, Babol University of Medical Science, Babol, I.R.Iran. , ma_ghasempour_ir@yahoo.com | 
								
								
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                                  Abstract:       (2783 Views)  | 
								
								
								  Background and Objective: Matrix metalloproteinases (MMPs) reduces the resin-dentin bond and bond strength over time. One of the substances introduced as MMps inhibitors is omega-9. This study aims to investigate the effect of pretreatment of dentin with omega-9 and chlorhexidine (CHX) on the durability of bond strength in certain time intervals and modes of failure. 
Methods: In this laboratory study, 45 permanent third molar teeth without caries were cut with a disc to expose the dentin of the middle part of the crown. Then, they were randomly divided into three groups: without pretreatment, pretreatment with CHX, and with Omega 9. This experiment was done after etching and before placing Single bond 2. Each group was divided into three subgroups, one day, 3 months and 6 months. A 4mm composite block was placed on the tooth and then cut into dimensions of 1×1 mm and microtensile bond strength test was performed. The failure mode was examined by stereo microscope using X40 magnification. 
Findings: In the comparison of pretreatment groups with CHX and Omega-9, there was no significant increase in bond strength after 24 hours. After three months, the bond strength in the pretreatment group with CHX (13.40±2.64 MPa) was significantly higher compared to the control group (10.46±3.5 MPa) (p=0.014). Moreover, in the omega-9 pretreatment group, the bond strength (13.16±2.7 MPa) was significantly higher compared to the control group (10.46±3.5 MPa) (p=0.028). Average microtensile bond strength in the Omega 9 and CHX groups decreased after six months compared to three-month period but increased compared to the one-day period, which was not significant. 
Conclusion: Pretreatment with omega-9 increases the strength of the resin-dentin bond, and this increase was present for up to 3 months.  | 
								
								
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								  | Keywords:  Matrix Metalloproteinase, Tensile Strength, Adhesive Factors, Omega-9, Chlorhexidine. | 
								
								
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                                  Type of Study:  Experimental |
                                  Subject: 
                                  Dentistry (pediatrics)   Received: 2023/01/19 | Accepted: 2023/05/7 | Published: 2024/06/19
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