per
Journal of Babol University Of Medical Sciences
Journal of Babol University of Medical Sciences
1561-4107
2251-7170
2018-06
20
6
7
13
article
The Effect of Kangaroo Mother Care on Mental Health of Mothers with Premature Infants
Y Zahed pasha
yzpasha@gmail.com
1
A Salarmanesh
Myth_salarmanesh@yahoo.com
2
S Khafri
khafri@yahoo.com
3
S Mouodi
sussan.mouodi@gmail.com
4
A Arzani
ARZANIAF@GMAIL.COM
5
1. Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R.Iran
2. Student Research Committee, Babol University of Medical Sciences, Nursing ;Medwifery Faculty, Babol, I.R.Iran
3. Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R.Iran
4. Neuroscience Research Center, Health Research Institute, Department of Psychiatry, Babol University of Medical Science, Babol, I.R.Iran
5. Nursing Care Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R.Iran
BACKGROUND AND OBJECTIVE: Mothers with premature infants experience high levels of psychological stress. Considering the importance of maternal mental health as a parent-child care provider, this study was conducted to evaluate the effectiveness of Kangaroo Mother’s Care (KMC) of premature infant on mother’s mental health.
METHODS: In this quasi-experimental study, 60 mothers with premature infants (less than 37 weeks pregnant) admitted to Ayatollah Rohani Hospital, Babol University of Medical Sciences, were selected by non-random sampling method. They divided into two study groups marked as experimental group (n=30) and control group (n=30). Data were collected using the demographic questionnaire and General Health of Goldberg & Hiller questionnaire. The 28-item questionnaire consisted of 4 sub-scales: physical symptoms, anxiety and sleep symptoms, social function, and depression symptoms. A score of over 22 indicates a symptom of the disease. In the intervention group, mothers spent at least 2 hours, 3 to 4 times a day for one week. The control group had the current process in the care. The questionnaire was completed at the beginning and one month after the admission of the newborn in both groups and the data were compared.
FINDINGS: Finding showed that the overall mental health score in the intervention group before and after maternal care was (28.77±13.09) to (13.66±6.5) and in the control group (30.86±15.97) to (20.99±8.89) that this difference was significant (p<0.01). In relation to the scales in the intervention and control groups, respectively, the anxiety and sleep patterns (3.7±1.5 in contrast to 5.67±3.39), social function disorder (5.9±2.58 vs 7.21±2.2) Physical symptoms (2.13±1.88 vs. 5.2±3.31) had a significant difference between the two groups (p<0.05), but in the case of depressive symptoms (1.03±0.3) vs 2.7±2.31), this difference was not significant (p>0.05).
CONCLUSION: Regarding the results of this research, use of Kangaroo Mother’s Care (KMC) for improve of premature infant on mother’s mental health is step for health family.
http://jbums.org/article-1-7433-en.pdf
Kangaroo Mother’s Care (KMC)
Mental Health
Premature
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Journal of Babol University Of Medical Sciences
Journal of Babol University of Medical Sciences
1561-4107
2251-7170
2018-06
20
6
14
19
article
Comparison between the Effects of Green and Black Tea, and Fluoride on Microhardness and Prevention of Demineralization of Deciduous Teeth Enamel
M Bozorgi
dent_m1991@yahoo.com
1
M Ghasempour
ma_ghasempour@yahoo.com
2
Gh Ahmadi
gazalehahmadidds@gmail.com
3
S Khafri
khafri@yahoo.com
4
1. Student Research Committee, Babol University of Medical Sciences, Nursing ;Medwifery Faculty, Babol, I.R.Iran
2. Oral Health Research Center, Institute of Health, Babol University of Medical Sciences, Babol, I.R.Iran
3. Dental Materials Research Center, Institute of Health, Babol University of Medical Sciences, Babol, I.R.Iran
4. Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol I.R.Iran
BACKGROUND AND OBJECTIVE: Dental caries in preschool children impose serious problems on parents and children due to lack of cooperation. Since tea leaves contain fluoride and polyphenol, this study was conducted to compare the effects of green and black tea, and fluoride in preventing demineralization of deciduous teeth enamel.
METHODS: This experimental study was performed on 40 extracted human deciduous incisors. The teeth were divided into 4 groups of 10 and were then placed in distilled water, green tea, black tea and oral sodium fluoride (0.05%) for four minutes in seven consecutive days. Surface microhardness before and after tooth extraction was determined in these four solutions by Micro Vickers Hardness Testing Machine. To cause primary caries, each sample was kept for one week in demineralization solution and the concentrations of the released calcium, phosphorus and fluoride ions were analyzed by spectrophotometric and potentiometric laboratory methods.
FINDINGS: Primary microhardness showed no significant difference between the groups. Secondary microhardness compared to primary microhardness in the two groups of green tea (mean of 317 ± 65.47 to 386 ± 85.42, p = 0.003) and fluoride (mean of 319 ± 71.76 to 446 ± 117.15, p = 0.003) increased significantly. The concentration of calcium and phosphorus ions in the four study groups showed a significant difference after being placed in the demineralization solution (p = 0.001) (p = 0.003). However, this difference was not observed in fluoride concentrations.
CONCLUSION: The results of this study showed that drinking green tea can increase the microhardness and green and black tea increase the resistance to demineralization of the deciduous teeth enamel.
http://jbums.org/article-1-7340-en.pdf
Enamel
Microhardness
Green Tea
Black Tea
Demineralization
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Journal of Babol University Of Medical Sciences
Journal of Babol University of Medical Sciences
1561-4107
2251-7170
2018-06
20
6
20
26
article
Evaluating the Performance of Flow Cytometric Method in Identification of Platelet Resistance in Patients with Acute Myeloid Leukemia (AML)
M Ghorbani
mahdighorbani92@yahoo.com
1
MT Hojjati
mthhematology@gmail.com
2
1. Department of Laboratory Sciences, Faculty of Paramedicine, AJA University of Medical Sciences, Tehran, I.R.Iran
2. Laboratory Science Research Center, Golestan University of Medical Sciences, Gorgan, I.R.Iran
BACKGROUND AND OBJECTIVE: Immune platelet resistance is a condition in which antibodies are produced against platelet antigens and cause damage to injected platelets by phagocytes and macrophages. The aim of this study is to evaluate the efficacy of flow cytometry in predicting the results of platelet injections and platelet resistance and selecting compatible platelet for patients.
METHODS: This case-control study was performed on 15 patients with acute myeloid leukemia (AML) with two or multiple injections of platelets and 15 healthy subjects without a history of platelet injection. After marking the platelets with 5-Chloromethylfluorescein diacetate (CMFDA) and their adjacency to the serum of patients, the amount of phagocytosis of platelets by monocytes was assessed in the two groups.
FINDINGS: The mean phagocytic power of platelets by monocyte was 18.27 ± 2.86% in the control group, 68.47 ± 10.40% in the group of patients with immune platelet resistance, and 36.73 ± 15.21 in the group of patients without immune platelet resistance (p = 0.001). In addition, there was a significant negative correlation between phagocytic power of platelets by monocyte and Corrected Count Increment (CCI) at 1 and 24 hours (p = - 0.001).
CONCLUSION: Based on the results of this study and considering the high sensitivity of the flow cytometric method, the use of CMFDA is highly appropriate for evaluating platelet studies, and it can also be used for platelet crossmatch by flow cytometry.
http://jbums.org/article-1-7284-en.pdf
Platelet Resistance
Flow Cytometry
CCI
Phagocytosis
5-Chloromethylfluorescein diacetate
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Journal of Babol University Of Medical Sciences
Journal of Babol University of Medical Sciences
1561-4107
2251-7170
2018-06
20
6
27
35
article
Detection of Intercellular Adhesion (ica) Genes Involved in Biofilm and Slime Formation in Clinical Isolates of Staphylococcus Aureus Harboring mecA Gene
N Yousefi Nojookambari
nedausefie@gmail.com
1
S Yazdansetad
sajjad.yazdansetad@gmail.com
2
A Ardebili
ardebili-abdollah57@yahoo.com
3
M Saki
mortezasaki1981@gmail.com
4
E Najjari
e_najari
5
Infectious Diseases & Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
BACKGROUND AND OBJECTIVE: Prevalence of methicillin resistant Staphylococcus aureus (MRSA) strains is one of the most important health care problems and life-threatening in worldwide. The methicillin resistant S. aureus strains producing biofilm and slime have potential to colonize and transmit. The present study was conducted to detect intercellular adhesion (ica) genes involved in biofilm and slime formation in clinical isolates of methicillin resistant S. aureus harboring mecA gene.
METHODS: In this cross-sectional study, a total of 85 bacterial isolates suspected to S. aureus were prepared from clinical samples. The antibiotic susceptibility testing of bacteria to the penicillin, gentamicin, oxacillin, ciprofloxacin, ofloxacin and vancomycin was carried out based on disk diffusion agar method. Biofilm and slime formation of bacteria were examined by tissue culture polystyrene plate (TCP) and Congo red agar (CRA). The presence and frequency of icaA, icaD and mecA genes were detected by multiplex PCR.
FINDINGS: 45 out of 85 (52.94%) S. aureus isolates were resistant to the methicillin. All of methicillin resistant S. aureus were able to produce biofilm and slime. Consumedly surface hydrophobicity was seen in 55.55% and 100% of strains producing strong biofilm and slime, respectively. The icaA, icaD and mecA genes were present in all biofilm and slime producing isolates.
CONCLUSION: Our results showed that the all methicillin resistant S. aureus isolates with some abilities, including polysaccharide intercellular adhesion, bacterial attachment, biofilm and slime production were positive for icaA and icaD genes.
http://jbums.org/article-1-6925-en.pdf
Staphylococcus aureus
Biofilm
Slime
icaA
icaD
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Journal of Babol University Of Medical Sciences
Journal of Babol University of Medical Sciences
1561-4107
2251-7170
2018-06
20
6
36
40
article
Effect of Isolated Tricin from Arial Part of Allium atrovoilaceum Boiss. on Proliferation and Apoptosis in PC3 Cell Line
Z Lorigooini
zahralorigooini@gmail.com
1
S Ghasemi
sorayya.ghasemi@gmail.com
2
N Asgarian Dehkordi
mx_am1999@yahoo.com
3
M Motamedi
sorayya.ghasemi@gmail.com
4
Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran
2. Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, I.R.Iran
Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran
Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran
BACKGROUND AND OBJECTIVE: Tricin as a flavone compound, in many food sources, has anti-inflammatory and anti-proliferative effects in several cancer cell lines. Considering the importance of using natural anti-cancer drugs in treatment-resistant cancers such as prostate cancer, the aim of this study was to investigate the effect of tricin on cell growth and proliferation and induction of apoptosis in human PC3 prostate cancer cell line.
METHODS: In this experimental study, the PC3 cell line was prepared from the Pasteur Institute of Iran and cultivated. Extraction and purification of Tricin were performed using column chromatography and re-crystallization of Alliuum atrovoilaceum extract. The cytotoxic effect of Tricin in concentrations of 60,80,100,120, and 140 μM was evaluated by MTT method. Apoptotic effect was evaluated in the treated cell group with the IC50 concentration of Tricin and untreated cells (control group), using an Annexin-V kit and flow cytometry.
FINDINGS: The viability of cells at different tricin concentrations were 85.66±1.52, 76±3.60, 66.33±4.16, 44±3.60, and 36.66±3.21, respectively (p<0.01). The IC50 concentration of tricin was 117.5±4.4 μM for PC3 cell line. The apoptosis rate in PC3 cells after 48 hours of treatment with IC50 concentration of tricin was 24.3±0.58%, which was not significant in comparison with control cells (23.3±0.58%).
CONCLUSION: The results of this study showed that Tricin resulted in cell death in the PC3 cell line, but the cell death mechanism was not apoptosis.
http://jbums.org/article-1-7177-en.pdf
Prostate Cancer
Tricin
Apoptosis
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Journal of Babol University Of Medical Sciences
Journal of Babol University of Medical Sciences
1561-4107
2251-7170
2018-06
20
6
41
45
article
Prevalence of Soft Tissue Calcification in Panoramic Radiographs in Northern of Iran
M Safabakhsh
drmaryamsafabakhsh@yahoo.com
1
M Johari
johari.mrm@gmail.com
2
A Bijani
alibijani@yahoo.com
3
S Haghanifar
s.haghanifar@mubabol.ac.ir
4
1. Student Research Committee, Babol University of Medical Sciences, Babol, I.R.Iran
2. Dental Materials Research Center, Institute of Health, Babol University of Medical Sciences, Babol, I.R.Iran
3. Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R.Iran
4. Oral Health Research Center, Institute of Health, Babol University of Medical Sciences, Babol, I.R.Iran
BACKGROUND AND OBJECTIVE: Soft tissue calcification is a relatively common issue in panoramic radiography. Some of these calcifications may have non-specific clinical symptoms as feeling of foreign body, dysphagia, otalgia and non-reflective cough. Therefore, for correct diagnosis and avoiding incorrect and excess treatments it’s necessary to have information about prevalence of these calcifications in regional populations. This study aimed to determine the prevalence of soft tissue calcification in panoramic radiographs in a selected population in northern Iran.
METHODS: In this cross sectional study, panoramic radiographs of 5000 patients referring to Oral & Maxillofacial radiology department of Babol dental school from 2014 to 2017 were examined. Radiographs were evaluated for the presence of any calcification, and their prevalence and their relationship with age were evaluated in two groups of under and over 40 years of age and gender.
FINDING: The prevalence of the observed soft tissue calcifications including calcification of stylohyoid ligands was 484 cases (9.7%), tonsilolith 52 cases (1%), calcification of lymph nodes 9 cases (0.2%), calcification of carotid artery 22 cases (0.4%) and thyroid cartilage calcification was 17 cases (0.3%). No cases of rhinolith, antrolith, sialolith and phlebolitis were found. The amount of tonsilolith (34 to 18 cases) and lymph node calcification (7 versus 2 cases) were significantly higher in men. (p=0.002 and p =0.048).
Also, the prevalence of calcification of stylohyoid ligament (290 versus 194 cases) (p=0.001), tonsilolith (13% vs. 39 cases) (p=0.001), calcification of carotid artery (18 versus 4) (p=0.001), and thyroid (14 versus 3) (p=0.003) were significantly relevant with age.
CONCLUSION: The results of this study showed that soft tissue calcifications are prevalent and the most common is stylohyoid ligament calcification.
http://jbums.org/article-1-7719-en.pdf
Panoramic Radiography
Prevalence
Calcification of ligaments
Soft tissue
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Journal of Babol University Of Medical Sciences
Journal of Babol University of Medical Sciences
1561-4107
2251-7170
2018-06
20
6
46
52
article
Lack of Genetic Association between Interleukin-18 Gene Polymorphism (rs1946518) and Chronic Hepatitis B Infection
M Salehi
m.salehi.bio@gmail.com
1
SR Mohebbi
srmohebbi@gmail.com
2
M Karkhane
bbi@gmail.com
3
Sh Kazemian
bbi@gmail.com
4
P Azimzadeh
bbi@gmail.com
5
M Saeedi Niasar
bbi@gmail.com
6
A Sharifian
bbi@gmail.com
7
MR zali
bbi@gmail.com
8
1- Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- Gastroenterology and liver diseases research center, Research institute for gastroenterology and liver diseases, Shahid Beheshti university of medical Sciences, Tehran, Iran
1- Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- Gastroenterology and liver diseases research center, Research institute for gastroenterology and liver diseases, Shahid Beheshti university of medical Sciences, Tehran, Iran
Foodborne and waterborne diseases research center, Research institute for gastroenterology and liver diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- Gastroenterology and liver diseases research center, Research institute for gastroenterology and liver diseases, Shahid Beheshti university of medical Sciences, Tehran, Iran
2- Gastroenterology and liver diseases research center, Research institute for gastroenterology and liver diseases, Shahid Beheshti university of medical Sciences, Tehran, Iran
2- Gastroenterology and liver diseases research center, Research institute for gastroenterology and liver diseases, Shahid Beheshti university of medical Sciences, Tehran, Iran
BACKGROUND AND OBJECTIVE: Interleukin 18 is a member of the cytokines that play an important role in the Th1-mediated immune response by inducing interferon-gamma activity in collaboration with Interleukin-12 (IL-18). Interleukin 12 and Interleukin 18 can play an important role in purifying viruses. Considering the importance of IL-18, this study was conducted to investigate the relationship between Interleukin-18 Gene polymorphism (-607 C/A: rs1946518) and the susceptibility to chronic hepatitis B infection.
METHODS: In this case-control study, the genomic DNA of 115 patients with chronic hepatitis B (with positive results of HBsAg and Anti-HBcAb serology testing) and 115 non-HBV-infected controls (negative results of HBsAg and Anti-HbcAb serology testing and no history of liver disease) was extracted by salting-out method and the genotype of single-nucleotide polymorphism (-607 C / A: rs1946518) was sequenced using PCR-RFLP method.
FINDING: The genotype frequency of TT, GT, and GG in patients was 40%, 49.6%, and 10.4% in patients, and 41.7%, 42.6%, and 15.7% in the control group, respectively. No significant difference was found between the patients group and the control group.
CONCLUSION: Based on the results of this study, there was no clear relationship between IL-18 polymorphism and the potential for chronic hepatitis B infection. Therefore, this polymorphism cannot be a potential factor for chronic hepatitis B.
http://jbums.org/article-1-7360-en.pdf
Interleukin 18
Chronic Hepatitis
Hepatitis B Virus
Single-Nucleotide Polymorphism
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Journal of Babol University Of Medical Sciences
Journal of Babol University of Medical Sciences
1561-4107
2251-7170
2018-06
20
6
53
61
article
Obstacles and Challenges in the Use of Probiotics
S Sadeghi
s110_sadeghi@yahoo.com
1
F Jaberi Ansari
roialbiotech@gmail.com
2
H Jalili
h.jalili@ut.ac.ir
3
1. Department of Life Science Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran, I.R.Iran
2. Department of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, I.R.Iran
1. Department of Life Science Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran, I.R.Iran
BACKGROUND AND OBJECTIVE: Probiotics are living microorganisms whose adequate intake has shown healthful effects in the host body and have been suggested to have beneficial effects in the prevention and treatment of many diseases. This study was conducted to investigate the obstacles and challenges of probiotic products in the production process and their effects on human health.
METHODS: For data collection in this review article, articles containing one of the terms “probiotic”, “lactobacillus”, “bifidobacterium”, “biogenic amine” and “antibiotic resistance” from 1990 to 2017 were searched and reviewed at Thomson Reuters, Pubmed, Scopus, Science Direct and Islamic World Science Citation Center(ISC).
FINDING: Research has shown that systematic infections and chronic diseases, over-stimulation of the immune system, transfer of antibiotic resistance genes, production of biogenic amines and D-lactic acidosis, lack of survival and sustainability of microorganisms and ultimately the change in the taste and flavor of probiotic products are among the obstacles and challenges facing the production of probiotics. The use of bifidobacterium to transfer antibiotic resistance genes is safer than other microorganisms for the production of probiotic products.
CONCLUSION: Based on the results of this study, probiotics are only safe in healthy people, although they are very useful for human health, but their use in children, pregnant women and people with a weakened immune system causes infection.
http://jbums.org/article-1-7344-en.pdf
Probiotics
Lactobacillus
Bifidobacterium
Biogenic Amine
Antibiotic resistance.
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Journal of Babol University Of Medical Sciences
Journal of Babol University of Medical Sciences
1561-4107
2251-7170
2018-06
20
6
62
69
article
Preparation and Evaluation of Rivax Protein Loading in Chitosan Nanoparticles
D Sadeghi
davudsadeghi64@yahoo.com
1
F Ebrahimi
febrhimi@ihu.ac.ir
2
M Zeinoddini
zeinoddini@modares.ac.ir
3
Y Tarverdizadeh
yosof.tarverdizadeh@gmail.com
4
M Bakhshi
dawoodsadeghi64@yahoo.com
5
MJ Bageripor
mjbagerii@gmail.com
6
SM Agaii
mojtabaasefi@yahoo.com
7
1. Biology Research Center, Faculty of Basic Sciences, Imam Hossein University, Tehran, I.R.Iran
1. Biology Research Center, Faculty of Basic Sciences, Imam Hossein University, Tehran, I.R.Iran
2. Institute of Biotechnology and Science, Malek-Ashtar University of Technology, Tehran, I.R.Iran
1. Biology Research Center, Faculty of Basic Sciences, Imam Hossein University, Tehran, I.R.Iran
1. Biology Research Center, Faculty of Basic Sciences, Imam Hossein University, Tehran, I.R.Iran
1. Biology Research Center, Faculty of Basic Sciences, Imam Hossein University, Tehran, I.R.Iran
1. Biology Research Center, Faculty of Basic Sciences, Imam Hossein University, Tehran, I.R.Iran
BACKGROUND AND OBJECTIVE: Ricin toxin is a heterodimer glycoprotein which, due to its high toxicity, is used as a bioterrorism agent. Immunogenicity studies against ricin are now focused on two subunit vaccine candidates, including RiVax and RVEc. These studies have examined the vaccine candidate immunization as an alone and in combination with adjuvant, however, there is not a published study on the immunogenicity evaluation of the candidate vaccine through the delivery by nanoparticles. The aim of this study was preparation and evaluation of RiVax recombinant vaccine-loading in chitosan nanoparticles.
METHODS: In this experimental study, After transferring the RiVax gene to the bacterium, inducing the expression and purification of the RiVax protein by affinity chromatography column, the RiVax protein was loaded with Ionic Gelation method in chitosan nanoparticles. Then, the properties of nanoparticles including size, morphology, loading percentage and release pattern of RiVax protein from nanoparticles and stability of this protein during acidic loading conditions in nanoparticles by SDS-PAGE were evaluated. Also, Immunization study were performed on 3 mouse groups (n=4/group) by RiVax protein, Nanoparticles containing protein and phosphate buffer.
FINDING: The results of this study showed that the nanoparticles containing protein had a size of 178 nm and a Zeta potential of +27.8 MV and a polydispersity index of 0.193. Also, according to SDS-PAGE results, it was found that the RiVax recombinant protein was denatured during the process of preparing the chitosan nanoparticles.
CONCLUSION: The results of this study showed that the RiVax protein has been unstable in acidic conditions for the production of chitosan nanoparticles and Ionic Gelation method is not suitable for loading this protein in chitosan nanoparticles.
http://jbums.org/article-1-7429-en.pdf
Chitosan
Nanoparticles
RiVax
Vaccine
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Journal of Babol University Of Medical Sciences
Journal of Babol University of Medical Sciences
1561-4107
2251-7170
2018-06
20
6
70
75
article
Recovery of Acute Pulmonary Edema Following Drowning Due to Seizure: Report of Two Cases
P Amri
pamrimaleh@yahoo.com
1
Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R.Iran
BACKGROUND AND OBJECTIVE: Drowning is a process of respiratory impairment due to the full immersion under fluids that about one third of patients with drowning experience pulmonary edema. In this article, two patients with acute pulmonary edema after drowning due to seizure who were admitted to the ICU department at Ayatollah Rouhani Hospital in Babol have been presented.
CASE REPORT: An 18-year-old man with a history of epilepsy was drowned while swimming in the pool after a seizure. Due to hypoxia, he was treated with supplemental oxygen and NIV for 12 hours. After partial recovery, he was treated with oxygen for three days. The patient on the fourth day was discharged with a good general condition.
Second patient: An 36-year old man, with a previous history of brain trauma was drowned while swimming in the sea after a seizure. The patient was intubated due to severe hypoxemia despite administration of oxygen (pao2 = 44mmHg) and low blood pressure (BP = 80 / 50mmHg), and was transferred to ICU at Ayatollah Rouhani Hospital. The patient was treated for mechanical ventilation and positive end expiratory pressure (PEEP) for 12 days. After recovery, he was separated from the ventilator and was discharged on the 14th day.
CONCLUSION: In acute pulmonary edema after drowning, administration of oxygen and non-invasive ventilation is recommended. In the absence of response, tracheal intubation and invasive mechanical ventilation are recommended.
http://jbums.org/article-1-6962-en.pdf
Drowning
Acute pulmonary edema
Noninvasive Ventilation.