fa اثر آلودگی صوتی بر غلظت سرمی کورتیکواسترون و برخی پارامترهای هماتولوژیک در موش صحرایی نر فیزیولوژی Physiology تجربی Experimental <div style="direction: rtl"> <p dir="rtl" style="margin: 0cm 0cm 0.0001pt line-height: 16pt direction: rtl unicode-bidi: embed"><strong><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">سابقه و هدف</span></strong><strong><span dir="ltr" style="font-size: 10pt color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">:</span></strong><span dir="ltr" style="font-size: 10pt color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">آلودگی‌ صوتی بعنوان یک عامل استرس‌زا می‌تواند تغییرات فیزیولوژیکی و روانی مختلفی را در انسان ایجاد کند. این مطالعه با هدف بررسی اثر آلودگی صوتی بر غلظت سرمی کورتیکواسترون و برخی پارامترهای هماتولوژیک در موش صحرایی نر انجام شد</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">.</span><span dir="ltr" style="font-size: 10pt"><u1:p><!--stripped--><!--stripped--></u1:p></span></p> <p dir="rtl" style="margin: 0cm 0cm 0.0001pt line-height: 16pt direction: rtl unicode-bidi: embed text-align: start"><strong><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">مواد و روش ها</span></strong><strong><span dir="ltr" style="font-size: 10pt color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">:</span></strong><span dir="ltr" style="font-size: 10pt color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">در این مطالعه تجربی، تعداد 60 سر موش صحرایی نر نژاد ویستار بصورت تصادفی به دو گروه آزمایشی کوتاه</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">مدت (یک روز مواجهه) و بلندمدت (30 روز مواجهه)، هر کدام شامل یک گروه کنترل و 3 گروه آزمایشی 4، 8 و 12 ساعت مواجهه صوتی تقسیم شدند. حیوانات طبق برنامه مشخصی، در معرض صوت با شدت 100 دسی‌بل قرار گرفتند. در پایان، تغییرات غلظت سرمی کورتیکواسترون و پارامترهای هماتولوژیک خون مورد بررسی قرار گرفت</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">.<u1:p></u1:p></span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra'"><!--stripped--><!--stripped--></span></p> <p dir="rtl" style="margin: 0cm 0cm 0.0001pt line-height: 16pt direction: rtl unicode-bidi: embed text-align: start"><strong><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">یافته ­ها</span></strong><strong><span dir="ltr" style="font-size: 10pt color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">:</span></strong><span dir="ltr" style="font-size: 10pt color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">سطح سرمی کورتیکواسترون در گروه‌های 8 ساعت (3/19</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">5/36</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">ng/dl</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">) </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">و 12 ساعت (1/76</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">4/88</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">ng/dl</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">) </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">مواجهه بلندمدت با صوت، در مقایسه با گروه کنترل (0/53</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">1/08</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> ng/dl) </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">افزایش یافت (به ترتیب</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">p<0/01</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">و</span><span class="apple-converted-space"><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">p<0/001). </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">تعداد گلبول‌های قرمز در گروه‌ 8 ساعت (0/33</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">7/71</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">mm³</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> ) </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">و 12ساعت (0/69</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">8/22</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">mm³</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> ) </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">مواجهه صوتی بلندمدت، در مقایسه با گروه کنترل (0/16</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">6/24</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">mm³</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> ) </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">افزایش یافت (به ترتیب 0/05</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">p<</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">و</span><span dir="ltr" lang="AR-SA" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">p<0/01</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">). </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">غلظت هموگلوبین نیز در گروه‌ 8 ساعت (0/68</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">16/66</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">gr/dl</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> ) </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">و 12 ساعت (0/81</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">16/60</span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">gr/dl</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> ) </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">مواجهه صوتی بلندمدت، در مقایسه با گروه کنترل (0/66</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">14/15</span><span dir="ltr" lang="AR-SA" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">gr/dl</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">) </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">افزایش یافت</span><span dir="ltr" lang="AR-SA" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">(</span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">p<0/05</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">). </span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">همچنین هماتوکریت نیز در دو گروه‌ 8 ساعت (3/28</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">40/57) و 12ساعت (1/76</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">40/66) مواجهه صوتی بلندمدت، در مقایسه با گروه کنترل (3/13</span><span lang="AR-SA" style="font-size: 10pt font-family: Cambria, serif color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">±</span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">35/69) به طور معنی داری افزایش یافت</span><span dir="ltr" lang="AR-SA" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">(</span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">p<0/05</span></span><span dir="ltr" style="font-size: 10pt color: rgb(51, 51, 51) background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">).<u1:p></u1:p></span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra'"><!--stripped--><!--stripped--></span></p> <p dir="rtl" style="margin: 0cm 0cm 0.0001pt line-height: 16pt direction: rtl unicode-bidi: embed text-align: start"><strong><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">نتیجه</span></span></strong><strong><span dir="ltr" style="font-size: 10pt color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span></strong><strong><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">گیری</span></span></strong><strong><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span dir="ltr" style="font-size: 10pt color: blue background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">:</span> </span></strong><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">بر اساس نتایج این مطالعه</span><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"> </span></span><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra' background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">احتمالا مواجهه بلندمدت صوتی از طریق افزایش سطح کورتیکواسترون سرمی میتواند موجب افزایش تعداد گلبول‌های قرمز و برخی از پارامترهای هماتولوژیک خون ‌شود</span></span><span dir="ltr" style="font-size: 10pt background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial"><span style="background-image: initial background-attachment: initial background-size: initial background-origin: initial background-clip: initial background-position: initial background-repeat: initial">. </span></span><span lang="AR-SA" style="font-size: 10pt font-family: '2 Mitra'"><!--stripped--><!--stripped--></span></p> <p dir="rtl" style="margin: 0cm 0cm 0.0001pt line-height: 15.6pt direction: rtl unicode-bidi: embed"></p> <p class="MsoNormal" dir="rtl" style="line-height: 16pt"><span dir="ltr" style="font-size: 10pt"><!--stripped--> <!--stripped--></span></p> </div> <div> <p class="MsoNormal" style="line-height: 16pt direction: ltr unicode-bidi: embed"><font face="times new roman, times, serif"><b><span style="font-size: 10pt color: blue">BACKGROUND AND OBJECTIVE:</span></b><span style="font-size: 10pt"> </span><span style="font-size: 10pt">Sound pollution is one of the main causes of stress that could lead to several physiological and mental changes in humans. This study aimed to investigate the effects of sound pollution on the serum levels of corticosterone and other hematological parameters in male rats</span><span style="font-size: 10pt">. <!--stripped--><!--stripped--></span></font></p> <p class="MsoNormal" style="line-height: 16pt direction: ltr unicode-bidi: embed"><font face="times new roman, times, serif"><b><span style="font-size: 10pt color: blue">METHODS:</span></b><span style="font-size: 10pt"> </span><span style="font-size: 10pt">In this experimental study, 60 male Wistar rats were randomly divided into two groups of short-term experiment (one-day exposure) and long-term experiment (30-day exposure). Each group consisted of one control group and three experimental groups with 4, 8 and 12 hours of exposure to noise pollution. According to a pre-designated schedule, the animals were exposed to 100 dB sound pressure, and changes in the serum levels of corticosterone and hematological parameters were recorded</span><span style="font-size: 10pt">.</span><span style="font-size: 10pt"> </span><span style="font-size: 10pt"><!--stripped--><!--stripped--></span></font></p> <p class="MsoNormal" style="line-height: 16pt direction: ltr unicode-bidi: embed"><font face="times new roman, times, serif"><b><span style="font-size: 10pt color: blue">FINDINGS:</span></b><span style="font-size: 10pt"> </span><span style="font-size: 10pt">In this study, serum levels of corticosterone increased in the long-term exposure group (8 hours: 5.36</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">3.19 ng/dl, 12 hours: 4.88</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">1.76 ng/dl) compared to the control group (1.08</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">0.53 ng/dl) (p<0.01 and p<0.001, respectively). Number of red blood cells also increased in the long-term exposure group (8 hours: 7.71</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">0.33 mm³, 12 hours: 8.22</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">0.69 mm³) compared to the control group (6.24</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">0.16 mm³) (p<0.05 and p<0.01, respectively). In addition, there was an increase in hemoglobin concentration in the long-term exposure group (8 hours: 16.66</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">0.68 gr/dl, 12 hours: 16.60</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">0.81gr/dl) compared to the control group (14.15</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">0.66 gr/dl) (p<0.05). Moreover, there was a significant increase in the hematocrit in the two groups of 8 hours (40.57</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">3.28) and 12 hours (40.66</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">1.76) of long-term exposure compared to the control group (35.69</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt letter-spacing: -0.3pt">±</span><span style="font-size: 10pt letter-spacing: -0.3pt">3.13) (p<0.05).</span><span dir="rtl" lang="AR-SA" style="font-size: 10pt"><!--stripped--><!--stripped--></span></font></p> <font face="times new roman, times, serif"><b><span style="font-size: 10pt color: blue">CONCLUSION:</span></b><span style="font-size: 10pt"> </span><span style="font-size: 10pt">According to the results of this study, long-term exposure to noise pollution could increase the number of red blood cells and other hematological parameters by raising the serum levels of corticosterone</span></font></div> <div></div> واژه های کلیدی: آلودگی صوتی, کورتیکواسترون, شمارش کامل سلول های خونی, رت  Sound Pollution, Corticosterone, Complete Blood Cell Count, Rat 41 47 http://jbums.org/browse.php?a_code=A-10-1754-1&slc_lang=fa&sid=1 Samad Nazemi صمد ناظمی samadnazemi@gmail.com 100319475328460012922 100319475328460012922 No Akbar Pejhan اکبر پژهان mojadadi@gmail.com 100319475328460012923 100319475328460012923 No Hassan Azhdari-Zarmehri حسن اژدری زرمهری mojadadi@gmail.com 100319475328460012924 100319475328460012924 No Mohammad Shafi Mojadadi محمدشفیع مجددی mojadadi@gmail.com 100319475328460012925 100319475328460012925 Yes