fa تاثیرآفت کش های ارگانوفسفره روی باروری بیوشیمی Biochemical تحقیقی Research <p><font face="Times New Roman" size="3"> </font></p><p class="MsoNormal" style="margin: 0in 0in 0pt text-align: justify line-height: 16pt text-justify: kashida text-kashida: 0% mso-line-height-rule: exactly" dir="rtl"><font size="2"><b><span lang="FA" style="color: blue font-family: "2 Mitra" mso-bidi-font-size: 10.0pt">سابقه و هدف:</span></b><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt"> ارگانوفسفره ها،</span><span class="hps"><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt mso-ascii-font-family: Arial mso-hansi-font-family: Arial"> برای از بین بردن علف های هرز، جوندگان، موجودات آسیب رسان و دفع</span></span><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt mso-ascii-font-family: Arial mso-hansi-font-family: Arial"> حشرات <span class="hps"><font face="Times New Roman">و</font></span> قارچ ها، <span class="hps"><font face="Times New Roman">طراحی شده اند. </font></span></span><span class="nowrap2"><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt">بیشترین تاثیر ارگانوفسفره ها بر روی سیستم ایمنی بدن و دستگاه تولید مثلی است. مطالعه حاضر تاثیر آن را بر روی سیستم باروری مورد بررسی قرار می دهد.</span></span><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt mso-ascii-font-family: Arial mso-hansi-font-family: Arial"> </span><b><span lang="FA" style="color: blue font-family: "2 Mitra" mso-bidi-font-size: 10.0pt"><o:p /></span></b></font></p><p><font face="Times New Roman" size="3"> </font></p><p class="MsoNormal" style="margin: 0in 0in 0pt text-align: justify line-height: 16pt text-justify: kashida text-kashida: 0% mso-line-height-rule: exactly" dir="rtl"><font size="2"><b><span lang="FA" style="color: blue font-family: "2 Mitra" mso-bidi-font-size: 10.0pt">مواد و روشها:</span></b><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt"> </span><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt mso-ascii-font-family: Arial mso-hansi-font-family: Arial">در این مطالعه با استفاده </span><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt">از بانک اطلاعاتی و معتبر </span><font face="Times New Roman"><span style="mso-bidi-font-size: 10.0pt mso-bidi-font-family: "2 Mitra"" dir="ltr">NCBI</span><span dir="rtl"></span><span dir="rtl"></span></font><span style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt mso-ascii-font-family: Arial mso-hansi-font-family: Arial"><span dir="rtl"></span><span dir="rtl"></span> <span lang="FA"><font face="Times New Roman">مقالاتی که در زمینه سموم ارگانوفسفره و تاثیرات سوئی که بر روی بافت های بدن و ارگانهایی مثل سیستم تناسلی داشتند و مقا</font></span></span><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt">لات مختلف در خصوص سموم کشاورزی و ناباروری استخراج گردید. </span><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt mso-ascii-font-family: Arial mso-hansi-font-family: Arial">مطالعاتی که در خصوص تاثیر سموم ارگانوفسفره بر کیفیت اسپرم و تخمک و نقش گلخانه ای سموم و تاثیر آنها انجام شده بود، مورد استفاده قرار گرفتند.</span><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt"> <b><span style="color: blue"><o:p /></span></b></span></font></p><p><font face="Times New Roman" size="3"> </font></p><p class="MsoNormal" style="margin: 0in 0in 0pt text-align: justify line-height: 16pt mso-line-height-rule: exactly" dir="rtl"><font size="2"><b><span lang="FA" style="color: blue font-family: "2 Mitra" mso-bidi-font-size: 10.0pt">یافته ها:</span></b><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt"> </span></font><a name="OLE_LINK4"></a><a name="OLE_LINK3"><span style="mso-bookmark: OLE_LINK4"><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt mso-ascii-font-family: Arial mso-hansi-font-family: Arial"><font size="2">سمیت ژنتیکی، اختلال در <font face="Times New Roman"><span class="hps">غدد درون ریز و مسمومیت های ایمنی، از </span>علائم و نشانه های<span class="hps"> دراز مدت ارگانوفسفره ها بوده و به نوع و </span>میزان تماس با آن <span class="hps">بستگی دارد</span></font>. واکنش <span class="hps"><font face="Times New Roman">پوستی، تحریک دستگاه تنفسی</font></span></font></span></span></a><font size="2"><span style="mso-bookmark: OLE_LINK3"><span style="mso-bookmark: OLE_LINK4"><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt">،</span></span></span><span style="mso-bookmark: OLE_LINK3"><span style="mso-bookmark: OLE_LINK4"><span class="hps"><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt mso-ascii-font-family: Arial mso-hansi-font-family: Arial"> پاسخ های آلرژیک و مشکلات عصبی از جمله عوارض</span></span></span></span><span style="mso-bookmark: OLE_LINK3"><span style="mso-bookmark: OLE_LINK4"><span class="nowrap2"><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt mso-ascii-font-family: Arial mso-hansi-font-family: Arial"> آن هستند. </span></span></span></span><span style="mso-bookmark: OLE_LINK3"><span style="mso-bookmark: OLE_LINK4"><span class="nowrap2"><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt">فرآیند بیوشیمیایی و انتقال مواد در سلول ها، ممکن است در تماس با آن دچار اختلال شوند.</span></span></span></span><span style="mso-bookmark: OLE_LINK3"><span style="mso-bookmark: OLE_LINK4"><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt mso-ascii-font-family: TimesNewRomanPSMT mso-hansi-font-family: TimesNewRomanPSMT"> تخریب بافت بیضه و نارسایی در تخمدان و</span></span></span><span style="mso-bookmark: OLE_LINK3"><span style="mso-bookmark: OLE_LINK4"><span lang="FA" style="font-family: "2 Mitra" mso-bidi-font-size: 10.0pt"> اختلال هورمونی نیز در ارتباط با انواع آفت کش ها وجود دارد. </span></span></span><span lang="FA" style="color: blue font-family: "2 Mitra" mso-bidi-font-size: 10.0pt"><o:p /></span></font></p><p><font face="Times New Roman"><font size="3"> </font><b><span lang="FA" style="color: blue font-family: "2 Mitra" font-size: 10pt mso-ascii-font-family: "Times New Roman" mso-hansi-font-family: "Times New Roman" mso-fareast-font-family: "Times New Roman" mso-bidi-language: FA mso-no-proof: yes mso-ansi-language: EN-US mso-fareast-language: EN-US" dir="rtl">نتیجه گیری:</span></b></font><span lang="FA" style="font-family: "2 Mitra" font-size: 10pt mso-ascii-font-family: "Times New Roman" mso-hansi-font-family: "Times New Roman" mso-fareast-font-family: "Times New Roman" mso-bidi-language: FA mso-no-proof: yes mso-ansi-language: EN-US mso-fareast-language: EN-US" dir="rtl"> آگاهی از تاثیرات بالقوه زیان بار آفت کش ها بر روی باروری و سرانجام حاملگی باید در میان افرادی که از نظر شغلی در تماس با این آفت کش ها قرار دارند، افزایش پیدا کند.</span><span lang="FA" style="font-family: "2 Mitra" font-size: 10pt mso-ascii-font-family: Tahoma mso-hansi-font-family: Tahoma mso-fareast-font-family: "Times New Roman" mso-bidi-language: FA mso-no-proof: yes mso-ansi-language: EN-US mso-fareast-language: EN-US" dir="rtl"> همچنین مشاوره به آنها کمک می کند تا تماس خود با این آفت کش ها را به حداقل برسانند</span></p> <font face="Times New Roman" size="3"> </font><p class="MsoNormal" style="margin: 0in 0in 0pt text-align: justify line-height: 16pt unicode-bidi: embed direction: ltr mso-line-height-rule: exactly"><font size="2"><font face="Times New Roman"><b><span style="color: blue mso-bidi-font-size: 10.0pt mso-bidi-font-family: "Times New Roman"">BACKGROUND AND OBJECTIVE:</span></b><span style="mso-bidi-font-size: 10.0pt mso-bidi-font-family: "Times New Roman""> <span style="color: black">Organophosphates are designed to eliminate weeds, rodents, and harmful organisms and to repel insects and fungi. The greatest impact of organophosphates is on the immune system and reproductive organ. The present study was conducted to investigate the effect of organophosphates on fertility.<o:p /></span></span></font></font></p><font face="Times New Roman" size="3"> </font><p class="MsoNormal" style="margin: 0in 0in 0pt text-align: justify line-height: 16pt unicode-bidi: embed direction: ltr mso-line-height-rule: exactly tab-stops: 147.75pt"><font size="2"><font face="Times New Roman"><b><span style="color: blue mso-bidi-font-size: 10.0pt mso-bidi-font-family: "Times New Roman"">METHODS:</span></b><span style="mso-bidi-font-size: 10.0pt mso-fareast-font-family: Calibri mso-bidi-font-family: "Times New Roman""> </span><span style="mso-bidi-font-size: 10.0pt mso-bidi-font-family: "Times New Roman"">In this study, the articles on organophosphate pesticides and their adverse effects on body tissues and organs, such as reproductive system and different articles about agricultural pesticides and infertility were extracted from NCBI database. The studies conducted about the effect of organophosphate pesticides on the quality of sperm and ovum, greenhouse role of pesticides, and their effect were used.<o:p /></span></font></font></p><font face="Times New Roman" size="3"> </font><p class="MsoNormal" style="margin: 0in 0in 0pt text-align: justify line-height: 16pt unicode-bidi: embed direction: ltr mso-line-height-rule: exactly"><font size="2"><font face="Times New Roman"><b><span style="color: blue mso-bidi-font-size: 10.0pt mso-bidi-font-family: "Times New Roman"">FINDINGS:</span></b><span style="mso-bidi-font-size: 10.0pt mso-bidi-font-family: Mitra mso-bidi-language: AR-SA"> </span><span style="mso-bidi-font-size: 10.0pt mso-bidi-font-family: "Times New Roman"">Genetic toxicity, endocrinology disorder, and immune toxicities are the <a name="OLE_LINK1">long-term signs and symptoms</a> of organophosphates which depend on the type and amount of contact with them. Skin reaction, respiratory system stimulation, allergic responses, and neural problems are some of their complications. Biochemical process and material transfer in cells may be disturbed in contact with it. There is also testicular tissue damage, ovarian failure, and hormonal disorder associated with a variety of pesticides.<o:p /></span></font></font></p><font face="Times New Roman"><font size="3"> </font><b><span style="color: blue font-family: "Times New Roman","serif" font-size: 10pt mso-fareast-font-family: "Times New Roman" mso-bidi-language: FA mso-no-proof: yes mso-ansi-language: EN-US mso-fareast-language: EN-US">CONCLUSION:</span></b><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-fareast-font-family: "Times New Roman" mso-bidi-font-family: Mitra mso-bidi-language: AR-SA mso-no-proof: yes mso-ansi-language: EN-US mso-fareast-language: EN-US"> </span><span style="font-family: "Times New Roman","serif" font-size: 10pt mso-fareast-font-family: Calibri mso-bidi-language: FA mso-no-proof: yes mso-ansi-language: EN-US mso-fareast-language: EN-US">Awareness of the potential harmful impacts of pesticides on fertility and finally on pregnancy must increase among the people who considering their job, are in contact with these pesticides. Consulting them will also help them minimize their contact with these pesticides</span></font> سموم ارگانوفسفره, بیضه, تخمدان, هورمون های جنسی, ناباروری Organophosphate pesticides, Testis, Ovary, Sexual hormone, Infertility. 7 14 http://jbums.org/browse.php?a_code=A-10-1370-996&slc_lang=fa&sid=1 M. Gholamitabar Tabari (MSc) سیدغلامعلی جورسرایی 10031947532846006253 10031947532846006253 Yes مرکز تحقیقات باروری و ناباروری، حضرت فاطمه الزهرا (س)، دانشگاه علوم پزشکی بابل S.G.A. Jorsaraei (PhD) مریم غلامی تبار طبری 10031947532846006254 10031947532846006254 No مرکز تحقیقات باروری و ناباروری، حضرت فاطمه الزهرا (س)، دانشگاه علوم پزشکی بابل