[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
Site Facilities::
Ethics::
peer-review::
Indexing::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Journal DOI

AWT IMAGE

..
Copyright Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 
This Journal is licensed under a Creative Commons Attribution-NonCommercial 4.0
..
:: Volume 22, Issue 1 (3-2020) ::
J Babol Univ Med Sci. 2020; Volume 22 Back to browse issues page
A Case Report of Recurrent Cerebral Hydatid Cyst; Interaction between Phenytoin and Albendazole
E Vafadar Moradi * , M Talebi Doluee , B Rezavani Kakhki , B Abbasi , B Chaeedeh , H Baharvahdat
1. Department of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, I.R.Iran , vafadarme@mums.ac.ir
Abstract:   (2170 Views)
BACKGROUND AND OBJECTIVE: Hydatidosis is possible in all organs. However, brain involvement is only observed in only 1-2% of patients and is very rare. Common symptoms of brain involvement include headache, vomiting, seizures, behavioral disorders, or unilateral symptoms such as paralysis of one half of the body. Here we present a patient with cerebral hydatidosis that has recurred due to drug interactions between phenytoin and albendazole.
CASE REPORT: The patient is a 19 -year- old man with a history of cerebral hydatidosis who underwent two surgeries with complaints of generalized tonic-clonic seizures. CT scan of the brain showed a lobule cyst with internal septa in the right hemisphere of the brain with an adjacent lesion that has wall calcification, suggesting cerebral hydatidosis. To control the patient s seizures, sodium valproate was substituted for phenytoin and oral albendazole was recommended in consultation with the Infectious Diseases Service. The patient was discharged after five days in good general condition.
CONCLUSION: According to this case, concomitant use of anticonvulsant drugs including phenytoin, phenobarbital, and carbamazepine with albendazole has been reported to reduce plasma levels of albendazole and reduce its efficacy. Therefore, to control seizures in patients with cerebral hydatidosis treated with albendazole, it is better to use other anticonvulsant drugs.
Keywords: Seizures, Cerebral Hydatidosis, Albendazole, Phenytoin.
Full-Text [PDF 197 kb]   (881 Downloads)    
Type of Study: case report | Subject: Emergency Medicine
Received: 2019/12/14 | Accepted: 2020/06/23 | Published: 2020/11/7
Send email to the article author



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Vafadar Moradi E, Talebi Doluee M, Rezavani Kakhki B, Abbasi B, Chaeedeh B, Baharvahdat H. A Case Report of Recurrent Cerebral Hydatid Cyst; Interaction between Phenytoin and Albendazole. J Babol Univ Med Sci 2020; 22 (1) :304-307
URL: http://jbums.org/article-1-9148-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 22, Issue 1 (3-2020) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

The Journal of Babol University of Medical Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Persian site map - English site map - Created in 0.05 seconds with 43 queries by YEKTAWEB 4645