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:: Volume 19, Number 6 (6-2017) ::
Back to browse issues page JBUMS 2017, 19(6): 0-0
Evaluation of Bone Mineral Density in 6-14 Years Old Children with Asthma under treatment with Fluticasone
I Mohammadzadeh, S Fathollahpour, M Hajiahmadi, R Alizadeh-Navaei, M Amiri *
, alborz812002@yahoo.com
Abstract:   (136 Views)

Background and objectives: Inhaled corticosteroid, is used to treat and control of asthma and due to the effects of corticosteroids on bone mineral density; this study was done to determine the bone mineral density in children with asthma.

Materials and methods: This cross-sectional study was done on 6 to 14 years children with moderate to severe asthma at least one year treated was past with inhaled Fluticasone. Then all patients underwent bone densitometry. To measure bone density DEXA method was performed using a Hologic QDR4500. In this way lumbar spine and the femoral neck were evaluated and Z-score for each patient was recorded. In addition to the above information and dosage and duration of the disease were recorded for each patient.

Findings: The study was conducted on 62 children with asthma. The mean age of children was 2.1 ± 7.8 years, and 33 patients (53.2%) of them were male. Distribution The mean duration of asthma was 2.3 years and the mean value of FEV1 in patients with asthma was 77.3%. Osteopenia was seen in 5 patients (8.1%). There was not significant relation between gender (p=0.658) duration of consumption (p=1) and age (p=0.788), but there was significant relationship between the dose of Fluticasone with Osteopenia (p=0.007)

Conclusion: There was a significant percentage of Osteopenia in children with asthma, more than a year were treated with Fluticasone and there was a significant relationship between Fluticasone doses with Osteopenia.

Keywords: Asthma, inhaled corticosteroid, Bone Mineral Density
     
Type of Study: Cross Sectional | Subject: Alergy
Received: 2016/11/19 | Accepted: 2017/05/28 | Published: 2017/06/10
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Mohammadzadeh I, Fathollahpour S, Hajiahmadi M, Alizadeh-Navaei R, Amiri M. Evaluation of Bone Mineral Density in 6-14 Years Old Children with Asthma under treatment with Fluticasone. JBUMS. 2017; 19 (6)
URL: http://jbums.org/article-1-6454-en.html
Back to browse issues page Volume 19, Number 6 (6-2017)
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences
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