The Effects of Parenteral Fish Oil Administration in ICU Patients
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E. Sharifi (MSc) , S. Saraf-Bank (MSc) , L. Azadbakht (PhD) * |
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Abstract: (11608 Views) |
BACKGROUND AND
OBJECTIVE: Malnutrition is a prevalent problem among ICU patients.
After 3-4 days of hospitalization, many patients enter in a negative energy
balance. Early nutritional support is an effective way to improve clinical
outcomes in these patients. The type of fat emulsion in parentral nutrition is
effective on immune system function. There are several evidences emphasized on
the beneficial effects of fish oil based lipid emulsions. Regarding to
parenteral nutrition importance and the type of lipid emulsion, the aim of this
study was to review the effects of omega 3 administration among ICU patients. METHODS: We searched key words including omega 3, fish oil, and
parenteral nutrition in PubMed search engine. 354 papers were obtained. After
limiting to title/abstract and human
studies, finally 66 papers about sepsis, trauma and surgery was selected. FINDINGS: Fish
oil consumption change the Arachidonic acid metabolism. Most studies conducted
on septic and operated patients declared that fish oil consumption can improve
clinical outcomes and reduced the inflammatory markers. Furthermore several
studies confirmed the beneficial effects of fish oil consumption on length of
hospital stay and antibiotic requirement in multiple trauma or head injured
patients. CONCLUSION: It
seems that fish oil administration in ICU patients is associated with reduction
in inflammatory levels, shorter hospitalization period and improvement of other
clinical outcomes contributed to inflammation. |
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Keywords: Fish oil, Parenteral nutrition, ICU, Inflammation, Sepsis, Craniocerebral trauma, Digestive system surgical procedure. |
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Full-Text [PDF 500 kb]
(1952 Downloads)
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Type of Study: Research |
Subject:
Biochemical Received: 2013/01/30 | Accepted: 2013/07/10 | Published: 2014/08/9
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