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This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 
This Journal is licensed under a Creative Commons Attribution-NonCommercial 4.0
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:: Volume 3, Issue 2 (4-2001) ::
J Babol Univ Med Sci. 2001; Volume 3 Back to browse issues page
Aseptic meningitis after intravenous immunoglobulin (IVIG) infusion in children with immune thrombocytopenic purpura (ITP)
A Tamaddoni * , SA Fatemi , SM Miri
Abstract:   (12318 Views)
Objective: The most common cause of acute onset of bleeding in children is autoimmune thrombocytopenic purpura (ITP) that appears 1-4 weeks after viral infections with petechia, mucosal and gum bleeding. The cause of ITP is anti-platelet antibody IgG/IgM and one of the methods for its treatment is IVIG infusion. Case: The patient was a 11-year-old girl with purpura on her foot that were diffused on other parts of her body, especially on her high. At first time, by diagnosis ITP, the patient with a history of bleeding and arthritis in two stages with platelet counts 110000 and 72000 was treated with prednisone. When drugs were interrupted, complications replaced again. In second stage, she was hospitalized and treated with IVIG infusion (400 mg/kg/day). After 3 days with symptoms such as headache, vomiting, neck rigidity cast doubt on meningitis. Therefore, LP was done and CSF findings confirmed aseptic meningitis and using of antibiotics was recommended. Conclusion: IVIG infusion that is used for treatment of different diseases such as primary immunodeficiencies, infection in LBW infants and patients with CLL and ITP has different complications. Aseptic meningitis is one of the complications in patients who use this drug.
Keywords: Aseptic meningitis, intravenous immunoglobulin, Immune thrombocytopenic purpura
Full-Text [PDF 1050 kb]   (1770 Downloads)    
Type of Study: Research | Subject: Biochemical
Accepted: 2014/05/26 | Published: 2014/05/26


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Tamaddoni A, Fatemi S, Miri S. Aseptic meningitis after intravenous immunoglobulin (IVIG) infusion in children with immune thrombocytopenic purpura (ITP). J Babol Univ Med Sci 2001; 3 (2) :61-66
URL: http://jbums.org/article-1-2878-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 3, Issue 2 (4-2001) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

The Journal of Babol University of Medical Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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