[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
Site Facilities::
Ethics::
peer-review::
Indexing::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Journal DOI

AWT IMAGE

..
Copyright Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 
This Journal is licensed under a Creative Commons Attribution-NonCommercial 4.0
..
:: Volume 18, Issue 10 (10-2016) ::
J Babol Univ Med Sci. 2016; Volume 18 Back to browse issues page
The Relationship between Serum Copper Level with Cognitive Disorders in Elderly
ّ Kheirkhah , SR Hosseini * , S Azadforuz , H Parsian , H Rezaei , S Moaudi , A Bijani
Social Determinants of Health Research Center, Institute of Health, Babol University of Medical Sciences, Babol, I.R.Iran , hosseinirezaseyed@gmail.com
Abstract:   (5169 Views)

BACKGROUND AND OBJECTIVE: Copper is a metal element which plays a pivotal role in the pathology of various neurological disorders including cognitive disorders. Previous studies have shown different relationships between serum levels of copper and cognitive impairment. This study aimed to investigate the relationship between serum levels of copper and cognitive disorders in the elderly in Amirkola.

METHODS: This cross-sectional study is a part of Amirkola Health and Ageing Project performed on all the population is 60 years and older. According to the Mini-Mental State Examination (MMSE), people were divided into two groups with impaired cognitive status (N=347) and normal (N=657). People with cognitive impairment were classified in mild, moderate, severe subgroups. In this test, point more than or equal to 25 (30-25) was considered as natural and score less than 25 as a person with cognitive impairment. Serum copper level was measured in venous blood samples and was compared between two groups.

FINDINGS: In this study, of 1616 elderly people, 1004 people in the age group 60-90 years were examined. 518 men and 486 women were existed with a significant difference in serum level of copper between the sexes (p<0.0001). The average serum level of copper in people without cognitive impairment (129.43±54.83) was different from an average copper level in patients with cognitive impairment (135.06±57.38), but was not statistically significant. There was a significant difference in serum levels of copper in the MMSE subgroups (p=0.009).

CONCLUSION: The results showed that cognitive impairment is associated with serum levels of copper

Keywords: Cognitive Disorders, Elderly, Serum Level of Copper
Full-Text [PDF 273 kb]   (1623 Downloads)    
Type of Study: Cross Sectional | Subject: Neurology
Received: 2016/09/22 | Accepted: 2016/09/28 | Published: 2016/10/30
Send email to the article author



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Kheirkhah ّ, Hosseini S, Azadforuz S, Parsian H, Rezaei H, Moaudi S et al . The Relationship between Serum Copper Level with Cognitive Disorders in Elderly . J Babol Univ Med Sci 2016; 18 (10) :26-31
URL: http://jbums.org/article-1-6353-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 18, Issue 10 (10-2016) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی بابل Journal of Babol University of Medical Sciences

The Journal of Babol University of Medical Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Persian site map - English site map - Created in 0.06 seconds with 42 queries by YEKTAWEB 4645